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Eosinophilia in Pleural Effusions: a Speculative Negative Predictor for Malignancy
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 Title & Authors
Eosinophilia in Pleural Effusions: a Speculative Negative Predictor for Malignancy
Chu, Fang-Yeh; Liou, Ching-Biau; Sun, Jen-Tang; Bei, Chia-Hao; Liou, Tse-Hsuan; Tan, N-Chi; Yu, Yun-Chieh; Chang, Chih-Chun; Yen, Tzung-Hai; Su, Ming-Jang;
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Background: Eosinophilic pleural effusion (EPE) is an eosinophil count more than 10% on cytology of pleural samples. Recently, it was reported that malignancy had been the most prevalent cause inducing EPE. Therefore, we conducted an analysis on the prevalence and etiology of EPE and investigated the relationship between EPE and malignancy. Materials and Methods: Data for pleural cell differential count from patients receiving thoracentesis during the period from January 2008 to December 2013 were compared with clinical data and established diagnosis of patients obtained via electronic chart review. Results: A total of 6,801 requests of pleural cytology from 3,942 patients with pleural effusion who had received thoracentesis were available at Far Eastern Memorial Hospital from 2008 to 2013, and of these subjects, 115 (2.9%) were found to have EPE. The most frequent cause of EPE was malignancy (33.0%, n
Eosinophilic pleural effusion;lung cancer;malignancy;pleural fluid eosinophilia;
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