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Frequency of Cholelithiasis and Biliary Pathology in the Easter Island Rapanui and Non-Rapanui Populations
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 Title & Authors
Frequency of Cholelithiasis and Biliary Pathology in the Easter Island Rapanui and Non-Rapanui Populations
Bravo, Eduardo; Contardo, Jorge; Cea, Jerson;
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 Abstract
Background: Chile is one of the countries with the highest prevalence of cholelithiasis worldwide, considering the Mapuche ethnicity as a risk factor for developing this pathology. Moreover, cholelithiasis is the main risk factor for developing gallbladder cancer, being the fifth cause of cancer death in Chile. The purpose of this study was to compare the frequency of cholelithiasis and biliary pathology among the population belonging to Rapanui ethnicity and non-Rapanui population living on Easter Island. Materials and Methods: In this retrospective case-control study, a total of 609 abdominal ultrasonographs performed consecutively in Hanga Roa Hospital during the period August 2012 to January 2015 were analyzed. Multiple logistic regression was used to obtain odds ratio (OR) and 95% confidence intervals (95% CI) of cholelithiasis and biliary pathology, adjusting for age, gender and referral diagnostic hypothesis. Results: In the Rapanui population the frequency for cholelithiasis and biliary pathology was 6.4% and 13%, meanwhile for the non-Rapanui population it was 13% and 22% respectively. Compared to the non-Rapanui Chilean population, the Rapanui ethnicity presented an OR of 0.53 (95% CI: 0.29-0.95) for cholelithiasis and OR of 0.52 (95% CI: 0.33-0.82) for biliary pathology. Conclusions: We found statistically significant ethnic differences in the frequency of cholelithiasis and biliary disease among the population of Rapanui and non-Rapanui ethnicity, so that this could be a protective factor for the development of biliary pathology, given the Chilean population context. Other studies including community population to determine the real prevalence of cholelithiasis and analyze the protective role of Rapanui ethnicity on this disease are necessary.
 Keywords
Polynesia;cholelithiasis;biliary pathology;ethnic groups;Easter island;
 Language
English
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 References
1.
Arcos-Burgos M, Herrera P (2004). Analisis de mezcla genetica. In 'Poblaciones chilenas: cuatro decadas de investigaciones antropologicas'. Eds Rothhammer F and Llop E. Editorial Universitaria, Santiago, 241-67.

2.
Bortoff G, Chen M, Ott D, et al (2000). Gallbladder stones: imaging and intervention. Radio Graphics, 20, 751-66.

3.
Catan F, Altamirano C, Salas del CC, et al (2002). Ecografia realizada por cirujanos en el manejo de pacientes con trauma. Rev Med Chile, 130, 892-6.

4.
Del Carpio M, Mercapide C, Salvitti J, et al (2012). Early diagnosis, treatment and follow-up of cystic echinococcosis in remote rural areas in Patagonia: impact of ultrasound training of non-specialists. PLOS Negl Trop Dis, 6, 1444. crossref(new window)

5.
Drapkin I (1935). Contribucion al estudio antropologico y demografico de los Pascuenses. J de la Societe des Americanistes, 27, 265-302. crossref(new window)

6.
Englert S (2009). Aspecto fisico de la raza. In 'La tierra de Hotu Matua'. Ed Englert S. Rapa Nui Press, Easter Island, 203-25.

7.
Esquerra M, Roura P, Masat T, et al (2012). Ecografia abdominal: una herramienta diagnostica al alcance de los medicos de familia. Aten Primaria, 44, 576-85. crossref(new window)

8.
Instituto Nacional de Estadisticas, INE (Chile) (2015). Actualizacion de poblacion 2002 - 2012 y proyecciones 2013 - 2020 [Online]. http://www.ine.cl/canales/chile_estadistico/familias/demograficas_vitales.php.

9.
Latorre G, Ivanovic-Zuvic D, Corsi O, et al (2015). Cobertura de la estrategia preventiva de cancer de vesicula biliar en Chile: resultados de la Encuesta Nacional de Salud 2009 - 2010. Rev Med Chile, 143, 158-67. crossref(new window)

10.
McIntosh D, and Penney H (1980). Gray-scale ultrasonography as a screening procedure in the detection of gallbladder disease. Radiol, 136, 725-7. crossref(new window)

11.
Miquel J, Covarrubias C, Villarroel L, et al (1998). Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians and Maoris. Gastroenterol, 115, 937-46. crossref(new window)

12.
Rius E, Yaikin P, Contreras G (2013). Cancer prevalence in Easter Island population - 2006-2010. Asian Pac J Cancer Prev, 14, 3101-3. crossref(new window)

13.
Seguel G, Fres E, Frez M, et al (2007). Naturaleza de los polipos de la vesicula biliar sometidos a colecistectomia. Rev Chil Cir, 59, 208-11.

14.
Shea J, Berlin J, Escarce J, et al (1994). Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease. Arch Intern Med, 154, 2573-81. crossref(new window)

15.
Sippel S, Muruganandan K, Levine A, Shah S (2011). Review article: Use of ultrasound in the developing world. Int J Emerg Med, 4, 72. crossref(new window)

16.
Speets A, Hoes A, van der Graaf Y, et al (2006). Upper abdominal ultrasound in general practice: indications, diagnostic yield and consequences for patient management. Fam Pract, 23, 507-11. crossref(new window)

17.
Stambuk P (2010). Los mestizos. in 'rongo, la historia oculta de isla de pascua'. ed stambuk p. editorial pehuen, Santiago, 65-85.

18.
Steinmetz JP, and Berger JP (1999). Ultrasonography as an aid to diagnosis and treatment in a rural African hospital: a prospective study of 1,119 cases. Am J Trop Med Hyg, 60, 119-23.

19.
Wordsworth S, and Scott A (2002). Ultrasound scanning by general practitioners: is it worthwhile? J Public Health Med, 24, 88-94. crossref(new window)