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Evaluation of Cholangiocarcinoma Risk and its Related Factors In Wetland Geographical Communities of Ubon Ratchathani, Thailand
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 Title & Authors
Evaluation of Cholangiocarcinoma Risk and its Related Factors In Wetland Geographical Communities of Ubon Ratchathani, Thailand
Songserm, Nopparat; Woradet, Somkiattiyos; Bureelerd, Onanong; Charoenbut, Pattaraporn;
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 Abstract
Wetland geographical areas have a higher incidence of Opisthorchis viverrini-associated cholangiocarcinoma (CCA), confirmed by data from geographic information systems, than other areas. Behavioral data also indicate that people in these areas traditionally eat uncooked freshwater fish dishes, a vehicle for O. viverrini infection. The best approach to reducing CCA incidence is decreasing risk factors together with behavior alteration. Evaluation of CCA risk and its related factors are first needed for planning the prevention and control programs in the future. We therefore aimed to evaluate the CCA risk and explore its related factors among people in wetland communities of Ubon Ratchathani, Thailand. A cross-sectional study was conducted between July and August 2014. In total 906 participants, with informed consent, completed questionnaires. Overall risk of CCA was determined by multiplying odds ratios (ORs) of the risk factors for CCA from literature reviews. A mean score of 5.95 was applied as the cut-off point. Assessment of factors related to overall risk of CCA was accomplished using conditional logistic regression. Of all participants, 60.15% had a high level of the overall risk of CCA. Factors related to the overall risk of CCA were gender (p<0.001), marital status (p<0.001), perceived susceptibility (p
 Keywords
Cholangiocarcinoma;risk factors;wetland community;Ubon Ratchathani;Thailand;
 Language
English
 Cited by
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