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An Experimental Study on the Freeze Drying Process for Poly γ Glutamic Acid
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 Title & Authors
An Experimental Study on the Freeze Drying Process for Poly γ Glutamic Acid
Kang, Jisu; Sim, Yeon-Ho; Byun, Si-Ye; Chang, Young Soo; Kang, Byung Ha;
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This paper presents an experimental study on the freeze drying process for poly glutamic acid. The physical properties of poly glutamic acid are measured during the freeze-drying process. The moisture contents of poly glutamic acid according to the glass transient temperature are obtained by DSC (Differential Scanning Calorimetry) analysis. The end point of primary drying for the poly glutamic acid with a thickness of 3 mm is obtained by measuring the thickness of the dried layer, the amount of moisture evaporation, the moisture content, and the pressure in the drying vacuum chamber during the freeze-drying process. By considering the variation in the glass transient temperature with respect to the moisture content of the material, a control schedule for the heating plate temperature is suggested during the secondary drying process.
Vacuum freeze drying;Biomaterial;Poly glutamic acid;Glass transient temperature;
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