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Life Cycle Analysis of Stem Cell Technology Based on Diffusion Model : Focused on the Research Stage
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 Title & Authors
Life Cycle Analysis of Stem Cell Technology Based on Diffusion Model : Focused on the Research Stage
Jang, In-young; Hong, Jungsik; Kim, Taegu;
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Research on stem cells can be divided into three categories : pluripotent stem cell, adult stem cell, and induced pluripotent stem cell. Technology life cycle (TLC) on research stage is analyzed for the three stem cell categories based on diffusion model. Three diffusion models-logistic, Bass, and Bass model with integration constant (BMIC)-are applied to the number of articles related to each stem cell category in SCOPUS lists. Two different parameter estimation methods is used for each of logistic and Bass model. Results show that (1) the current year, 2015, lies in growth period at pluripotent stem cell and adult stem cell, and lies in growth period or maturity period at induced pluripotent stem cell. (2) Model fitness is the highest at BMIC model. (3) Imitation effect works best at the research area of induced pluripotent stem cell.
Stem cell;Technology life cycle;Diffusion model;Growth period;
 Cited by
An, X. Y. and Wu, Q. Q. (2011), Co-word analysis of the trends in stem cells field based on subject heading weighting, Scientometrics, 88(1), 133-144. crossref(new window)

Bass, F. M. (1969), A new-product growth model for consumer durables, Management science, 15, 215-227. crossref(new window)

Cantos-Mateos, G., Vargas-Quesada, B., Chinchilla-Rodriguez, Z., and Zulueta, M. A. (2012), Stem cell research : Bibliometric analysis of main research areas through KeyWords Plus, Aslib Proceedings : New Information Perspectives, 64(6), 561-590.

Choi, B. H. and Park, S. R. (2012), Current Status and Future Perspectives of Stem Cells and Regenerative Medicine, Hanyang Med Rev, 32(3), 127-133. crossref(new window)

Choi, H. S. and Hur, J. E. (2013), State of the art at stem cell based gene theraphy technology by patent analysis, 2013 Proceedings of Korea Technology Innovation Society, 14-14(Full manuscript :

Dani, C., Smith, A. G., Dessolin, S., Leroy, P., Staccini, L., Villageois, P., Darimont, C., and Ailhaud, G. (1997), Differentiation of embryonic stem cells into adipocytes in vitro, Journal of Cell Science, 110, 1279-1285.

Evans, M. J. and Kaufman, M. H. (1981), Establishment in culture of pluripotential cells from mouse embryos, Nature, 292, 154-156. crossref(new window)

Fraichard, A., Chassande, O., Bilbaut, G., Dehay, C., Savatier, P., and Samarut, J. (1995), In vitro differentiation of embryonic stem cells into glial cells and functional neurons, Journal of Cell Science, 108, 3181-3188.

Gao, L., Porter, A. L., Wang, J., Fang, S., Zhang, X., Ma, T., Wang, W., and Huang, L. (2013), Technology life cycle analysis method based on patent documents, Technological Forecasting and Social Change, 80, 398-407. crossref(new window)

Guo, X. (2014), A novel Bass-type model for product life cycle quantification using aggregate market data, International Journal of Production Economics, 158, 208-216. crossref(new window)

Hong, J. S. and Koo, H. Y. (2012), Comparison of the Bass Model and the Logistic Model from the Point of the Diffusion Theory, Journal of the Korean Operations Research and Management Science Society, 37(2), 113-125. crossref(new window)

Hong, J. S. and Eom, S. J. (2009), Two pieces extension of the Bass Diffusion Model, Journal of the Korean Operations Research and Management Science Society, 34(4), 15-26.

Hu, Q., Saunders, C., and Gebelt, M. (1997), Research Report : Diffusion of Information Systems Outsourcing : A Reevaluation of Influence Sources, Information Systems Research, 8(3), 288-301. crossref(new window)

Jarvenpaa, H. M., Makinen, S. J., and Seppanen, M. (2011), Patent and publishing activity sequence over a technology's life cycle, Technological Forecasting and Social Change, 78(2), 283-293. crossref(new window)

Kingsland, S. (1982), The Refractory Model : The Logistic Curve and the History of Population Ecology, The Quarterly Review of Biology, 57(1), 29-52.

Kim, T. G. and Hong, J. S. (2015), Bass model with integration constant and its applications on initial demand and left-truncated data, Technological Forecasting and Social Change, Forthcoming.

Kim, T. G. and Hong, J. S. (2015), Comparative Analysis of Box-office Related Statistics and Diffusion in Korea and US Film Markets, Korean Management Science Review, 32(1), 133-145. crossref(new window)

Koo, H. Y., Hong, J. S., and Kim, T. G. (2011), A Parameter Estimation of Bass Diffusion Model by the Hybrid of NLS and OLS, Journal of the Korean Institute of Industrial Engineers, 37(1), 74-82. crossref(new window)

Korea Research Institute of Bioscience and Biotechnology (2013), Stem Cell Research and Application of Technology.

Lee, Y. H., Kim, Y. E., and Park, J. A. (2008), Current status and prospects of induced pluripotent stem cells, Journal of Biomedical Research, 9(2), 5-11.

Li, L. L., Ding, G., Feng, N., Wang, M. H., and Ho, Y. S. (2009), Global stem cell research trend : Bibliometric analysis as a tool for mapping of trends from 1991 to 2006, Scientometrics, 80(1), 39-58. crossref(new window)

Martin, G. R. (1981), Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells, Proceedings of National Academy Sciences of United States of America, 78, 7634-7638. crossref(new window)

Meade, N. and Islam, T. (1995), Forecasting with growth curves : An empirical comparison, International Journal of Forecasting, 11(2), 199-215. crossref(new window)

Meade, N. and Islam, T. (1998), Technological Forecasting-Model Selection, Model Stability, and Combining Models, Management Science, 44(8), 1115-1130. crossref(new window)

Muller, E. and Yogev, G. (2006), When does the majority become a majority? Empirical analysis of the time at which main market adopters purchase the bulk of our sales, 73(9), Technological Forecasting and Social Change, 1107-1120. crossref(new window)

National Institute of Food and Drug Safety Evaluation (2015), Stem cell therapy development and regulatory trends 2014.

National Institutes of Health (NIH) Department of Health and Human Services (2001), Stem Cells-Scientific Progress and Future Research Directions.

Odorico, J. S., Kaufman, D. S., and Thomson, J. A. (2001), Multilineage differentiation from human embryonic stem cell lines, Stem Cells, 19, 193-204. crossref(new window)

Park, J. S. and Hong, J. J. (2013), Diffusion at the era of science and technology - Focused on newspaper citation pattern of stem cell market size, 2013 Proceedings of Korea Technology Innovation Society, 65-65(Full manuscript :

Potocnik, A. J., Nielsen, P. J., and Eichmann, K. (1994), In vitro generation of lymphoid precursors from embryonic stem cells, The Embo Journal, 13, 5274-5283.

Rohwedel, J., Maltsev, V., Bober, E., Arnold, H. H., Hescheler, J., and Wobus, A. M. (1994), Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo : developmentally regulated expression of myogenic determination genes and functional expression of ionic currents, Developmental Biology, 164, 87-101. crossref(new window)

Srinivasan, V. and Mason, C. H. (1986), Nonlinear Least Squares Estimation of New Product Diffusion Models, Marketing Science, 5(2), 169-178. crossref(new window)

Schmittlein, D. and Mahajan, V. (1982), Maximum Likelihood Estimation for an Innovation Diffusion Model of New Product Acceptance, Marketing Science, 1(1), 57-78. crossref(new window)

Takahashi, K. and Yamanaka, S. (2006), Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell, 126(4), 663-676. crossref(new window)

Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., and Jones, J. M. (1998), Embryonic stem cell lines derived from human blastocysts, Science, 282(5391), 1145-1147. crossref(new window)

Vierbuchen, T., Ostermeier, A., Pang, Z. P., Kokubu, Y., Sudhof, T. C., and Wernig, M. (2010), Direct conversion of fibroblasts to functional neurons by defined factors, Nature, 463(7284), 1035-1041. crossref(new window)

Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., Nie, J., Jonsdottir, G. A., Ruotti, V., Stewart, R., Slukvin, I. I., and Thomson, J. A. (2007), Induced pluripotent stem cell lines derived from human somatic cells, Science, 318(5858), 1917-1920. crossref(new window)

Zhao, D. and Strotmann, A. (2011), Intellectual structure of stem cell research : a comprehensive author co-citation analysis of a highly collaborative and multidisciplinary field, Scientometrics, 87(1), 115-131. crossref(new window)