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Friedewald-Estimated Versus Directly Measured LDL-Cholesterol: KNHANES 2009-2010
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 Title & Authors
Friedewald-Estimated Versus Directly Measured LDL-Cholesterol: KNHANES 2009-2010
Jang, Sungok; Lee, Jongseok;
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Low-density lipoprotein cholesterol (LDL-C) is a major modifiable risk factor for cardio- cerebrovascular disease. In clinical practice, however, it is primarily calculated using the Friedewald formula as a cost-effective method. The aim of this study was to compare Friedewald-estimated and directly measured LDL-C values and assess the concordance in guideline LDL-C risk classification between the two methods. The data were derived from the 2009 and 2010 Korea National Health and Nutrition Survey (KNHANES). Analysis was done for 4,319 subjects with lipid panels-total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), directly measured LDL-C using an enzymatic homogeneous assay, and triglycerides (TG). For subjects with TG lower than 400 mg/dL, Friedewald-estimated and directly measured LDL-C were highly correlated (r
Friedewald formula;Homogeneous assay;LDL-cholesterol;Validation;
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한국 성인의 이상지질혈증 유병률과 관리: 국민건강영양조사 2010-2012,장성옥;이종석;

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