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Antioxidant, Antimicrobial and Anticancer Properties of Seven Traditional Herb-combined Remedies
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  • Journal title : Journal of Life Science
  • Volume 25, Issue 4,  2015, pp.406-415
  • Publisher : Korean Society of Life Science
  • DOI : 10.5352/JLS.2015.25.4.406
 Title & Authors
Antioxidant, Antimicrobial and Anticancer Properties of Seven Traditional Herb-combined Remedies
Lee, Moon Hee; Lee, Jae-wang; Park, Cheol; Han, Min Ho; Hong, Su Hyun; Choi, Yung Hyun;
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In this study, we investigated the antioxidant activities and compared other physiological properties including anti-cancer and antimicrobial effects of several traditional Korean herb-combined remedies such as Gilgyung-tang (GGT), Daihwangmokdan-tang (DHMDT), Sagan-tang (SGT), Socheonryongtang (SCRT), Sihocheonggan-tang (SHCGT), Sipyukmiyuki-eum (SYMYKE) and Hwangheuk-san (HHS), which were recorded in “Dong-eui-bo-gam” for “Ongjeo”. Total phenolic contents of the herb medicines were in a rich order of GGT < SYMYKE < SCRT < SHCGT < DHMDT < SGT < HHS. Among them, HHS appeared highest in superoxide dismutase-like activity, ferric reducing antioxidant power, scavenging of 2,2’-diphenyl-1-picrylhydrazyl, and 2,2’-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical activity. Interestingly, there was a positive relationship between their total phenolic contents and their antioxidant activities. Although all of them showed anti-proliferative activities in human colon cancer HCT-116 cells, HHS was seven times higher than GGT. Antimicrobial activities against Escherichia coli and Helicobacter pylori were revealed only on SGT, SCRT, SYMYKE and HHS. Taken together, these findings reveal the potential use of traditional Korean herbal formulas as functional ingredients in antioxidant and physiological materials.
Anticancer activity;antimicrobial activity;antioxidant activity;traditional herb-combined remedies;
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