Advanced SearchSearch Tips
Irritation Fibroma Associated with Ectopic Eruption of the Maxillary Incisor
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Irritation Fibroma Associated with Ectopic Eruption of the Maxillary Incisor
Jeong, Younwook; Kang, Chungmin; Kim, Seunghye; Lee, Jaeho;
  PDF(new window)
Irritation fibroma is a common hyperplastic lesion of the oral mucosa that can occur in response to chronic irritation or trauma. This report presents an unusual case of irritation fibroma associated with ectopic eruption of the maxillary left central incisor in a patient with Angelman syndrome. Considering the patient`s medical history and cooperative ability, excisional biopsy under intramuscular sedation using midazolam was performed. The patient exhibited successful healing without lesion recurrence. It is important to perform histopathological examination followed by excisional biopsy, because other benign or malignant tumors may mimic the clinical appearance of an irritation fibroma.
Irritation fibroma;Excisional biopsy;Intramuscular sedation;Midazolam;Angelman syndrome;
 Cited by
Neville BW, Damm DD, Bouquot JE, et al. : Oral and maxillofacial pathology, 3rd ed., Saunders, 507-552, 2009.

Sapp JP, Eversole LR, Wysocki GP : Contemporary oral and maxillofacial pathology, 2nd ed., Mosby, 164-206, 1997.

Gross GE, Pfister H, Mittermayer C : Papilloma virus particles in a fibroma of the tongue. Acta Derm Venereol, 60:315-8, 1980.

Marx RE, Stern D : Oral and maxillofacial pathology: a rationale for diagnosis and treatment, 2nd ed., Quintessence Publishing Co, Inc., 399-466, 2012.

Korean academy of orofacial pain and oral medicine (Ed.) : Oral medicine Vol. III, Shinhung International, Inc., 121-9, 2010.

Pembrey M, Fennell SJ, Super M, et al. : The association of Angelman’s syndrome with deletions within 15q11-13. J Med Genet, 26:73-7, 1989.

Williams CA, Beaudet AL, Wagstaff J, et al. : Angelman syndrome 2005: updated consensus for diagnostic criteria. Am J Med Genet A, 140:413-8, 2006.

Marshall RI, Bartold PM : A clinical review of drug-induced gingival overgrowths. Aust Dent J, 44:219-32, 1999. crossref(new window)

Thompson AL, Herman WW, Konzelman J, Collins MA : Treating patients with drug-induced gingival overgrowth. J Dent Hyg, 78:1-13, 2004.

Prasad VN, Chawla HS, Singhi P, et al. : Folic acid and phenytoin induced gingival overgrowth-is there a preventive effect. J Indian Soc Pedod Prev Dent, 22:82-91, 2004.

Murakami C, Nahas Pires Correa MS, Nahas Pires Correa JP, et al. : Dental treatment of children with Angelman syndrome: a case report. Spec Care Dentist, 28:8-11, 2008. crossref(new window)

Kim BS, Yeo JS, Kim SO : Anesthesia of a dental patient with Angelman syndrome-A case report-. Korean J Anesthesiol, 58:207-10, 2010. crossref(new window)

Bernick S : Growths of the gingiva and palate; chronic inflammatory lesions. Oral Surg Oral Med Oral Pathol, 1:1029-41, 1948. crossref(new window)

Maryam S, Mohammadtaghi H, Soodabeh B : Localized lesions of oral cavity: a clinicopathological study of 107 cases. Research journal of medical sciences, 5:67-72, 2011. crossref(new window)

Bouquot JE, Gundlach KK : Oral exophytic lesions in 23,616 white Americans over 35 years of age. Oral Surg Oral Med Oral Pathol, 62:284-91, 1986. crossref(new window)

Buchner A, Calderon S, Ramon Y : Localized hyperplastic lesions of the gingiva: a clinicopathological study of 302 lesions. J Periodontol, 48:101-4, 1977. crossref(new window)

Ntomouchtsis A, Karakinaris G, Antoniades K, et al. : Benign lip lesions. A 10-year retrospective study. Oral Maxillofac Surg, 14:115-8, 2010. crossref(new window)

Christopoulos P, Sklavounou A, Patrikiou A : True fibroma of the oral mucosa: a case report. Int J Oral Maxillofac Surg, 23:98-9, 1994. crossref(new window)

Rotaru H, Choi JY, Kim SG, et al. : Transforming growth factor-alpha and oral fibroma: immunohistochemical and in situ hybridization study. J Oral Maxillofac Surg, 61:1449-54, 2003. crossref(new window)

Ryu MH, Kim BI, Kim J, et al. : Expression of TGF-${\beta}1$, MMP-1 and TIMP-1 in irritation fibroma. Kor J Oral Maxillofac Pathol, 33:61-8, 2009.

Dayan D, Bodner L, Wolman M, et al. : Histochemical characterization of collagen fibers in fibrous overgrowth (irritation fibroma) of the oral mucosa: effect of age and duration of lesion. Arch Gerontol Geriatr, 18:53-7, 1994. crossref(new window)

Mandel L, Baurmash H : Irritation fibroma. Report of a case. NY State Dent J, 36:344-7, 1970.

Toida M, Murakami T, Tatematsu N, et al. : Irritation fibroma of the oral mucosa: a clinicopathological study of 129 lesions in 124 cases. Oral Medicine and Pathology, 6:91-4, 2001. crossref(new window)