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Effects of Phytoncide-containing Cotton Fabrics on the Development of Atopic Dermatitis
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  • Journal title : Textile Science and Engineering
  • Volume 52, Issue 6,  2015, pp.388-395
  • Publisher : The Korean Fiber Society
  • DOI : 10.12772/TSE.2015.52.388
 Title & Authors
Effects of Phytoncide-containing Cotton Fabrics on the Development of Atopic Dermatitis
Kim, Eui Hwa;
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 Abstract
In this study, we investigated the effects of phytoncide-containing 100% cotton fabrics on the improvement of atopic dermatitis, through preclinical trials. The finishing agents used for testing were obtained by emulsification (S2), by capsulation (S4) using phytoncide extracted with supercritical , and by capsulation using solvent-extracted phytoncide (S3). The supercritically extracted phytoncide was used for in vitro testing. In the in vitro test, cytotoxicity occurred at the phytoncide concentrations of 0.1% and 0.5% in stained HaCaT cells and at 0.1% concentration in stained Raw 264.7 cells. In the in vivo test, the infiltration of inflammatory cells into skin tissue was significantly reduced in the S3 and S4 groups relative to the positive comparison group (Positive) of atopic dermatitis. Moreover, from results of the western blot and immunohistochemistry assays of tested skin tissue, we were able to confirm a reducing pattern of the markers related to keratogenesis.
 Keywords
atopic dermatitis;phytoncide;capsulation;emulsification;in vitro test;in vivo test;
 Language
Korean
 Cited by
 References
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