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Biological Monitoring of Workers Exposed to Diisocyanates using Urinary Diamines
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 Title & Authors
Biological Monitoring of Workers Exposed to Diisocyanates using Urinary Diamines
Lee, Jong Seong; Kim, Boowook; Shin, Jungah; Baek, JinEe; Shin, Jae Hoon; Kim, Ji-hye;
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Objectives: Diisocyanates are a potent inducer of diseases of the airways, especially asthma. In this study, toluenediamine(TDA) and methylenedianiline(MDA) in urine were evaluated as biomarkers of exposure to tolunenediisocyanate(TDI) and methylenediphenyl diisocyanate(MDI), respectively. Methods: Workers exposed to TDI and MDI, as well as non-occupationally exposed subjects, were studied and pre- and post-shift urine samples were collected from 8 control subjects and 8 workers from a factory which manufactures polyurethane products for reducing noise and vibration in automobiles. Airborne TDI and MDI(n
biological monitoring;methylenedianiline(MDA);methylenediphenyl diisocyanate(MDI);toluenediamine(TDA);tolunediisocyanate(TDI);
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