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Effect of Various Pear Cultivars at Different Fruit Development Stages on Antioxidant and Whitening Activities
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 Title & Authors
Effect of Various Pear Cultivars at Different Fruit Development Stages on Antioxidant and Whitening Activities
Yim, Sun-Hee; Cho, Kwang-Sik; Choi, Jin-Ho; Lee, Ju-Hyun; Kim, Myung-Su; Lee, ByulHaNa;
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 Abstract
This study was carried out to investigate the total polyphenols, antioxidant activities, and melanin synthesis inhibition of several pear cultivars (Pyruspyrifolia). The total polypenolic content of five pear cultivars was high in the unripe developmental stage. Total polyphenolic content of the Chuwhangbae cultivar extract was higher than that of other pear cultivars regardless of the developmental stage. However, the total flavonoid content did not differ between cultivars or developmental stages. The phenolic compound, arbutin has an inhibitory effect on melanogenesis. Arbutin levels in pear cultivars declined as the fruit matured. The free radical scavenging activity of the extract also decreased as the fruit ripened. In B16F10 mouse melanoma cells, most of the cultivar extracts inhibited melanin synthesis by about 50% at a concentration, except in the Gamcheonbae extract until 90 days after full bloom. We have confirmed that the extract of pear cultivars have antioxidant activity and skin-whitening effects.
 Keywords
arbutin;cytotoxicity;melanin;Pyrus pyrifolia;total polyphenolic content;
 Language
Korean
 Cited by
 References
1.
Kim EC, Ahn SY, Hong ES, Li GH, Kim EK, Row KH. Extraction of whitening agents from natural plants and whitening effect. Appl.Chem. Eng. 16: 348-353 (2005)

2.
Svobodova A, Psotova J, Walterova D. Natural phenolics in the prevention of UV-induced skin damage. Biomed. Pap. 147: 137-145 (2003) crossref(new window)

3.
Eberlein-Konig B, Placzek M, Przybilla B. Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-${\alpha}$-tocopherol (vitamin E). J. Am. Acad. Dermatol. 38: 45-48 (1998) crossref(new window)

4.
Takebayashi J, Ishii R, Chen J, Matsumoto T, Ishimi Y, Tai A. Reassessment of antioxidant activity of arbutin: Multifaceted evaluation using five antioxidant assay systems. Free Radical Res. 44: 473-478 (2010) crossref(new window)

5.
Tse TW. Hydroquinone for skin lightening: Safety profile, duration of use and when should we stop? J. Dermatol. Treat. 21: 272-275 (2010) crossref(new window)

6.
Zhu YZ, Huang SH, Tan BKH, Sun J, Whiteman M, Zhu YC. Antioxidants in Chinese herbal medicines: A biochemical perspective. Nat. Prod. Rep. 21: 478-489 (2004) crossref(new window)

7.
Bajpai VK, Yoon JI, Kang SC. Antioxidant and antidermatophytic activities of essential oil and extracts of Magnolia liliflora Desr. Food Chem. Toxicol. 47: 2606-2612 (2009) crossref(new window)

8.
Eun JB, Eo JH, Lee BD. Functional compounds and biological activity of Asian pear. Food Sci. Biotechnol. 45: 60-69 (2012)

9.
Petit L, Pirard GE. Skin-lightening products revisited. Int. J. Cosmetic Sci. 25: 169-181 (2003) crossref(new window)

10.
Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci. Technol. 28: 25-30 (1995) crossref(new window)

11.
Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Bio. Med. 26: 1231-1237 (1999) crossref(new window)

12.
Doh ES., Chang JP, Kil KJ, Choi MS, Yang JK, Yun CW, Jeong SM, Jung YH, Lee GH. Antioxidative activity and cytotoxicity of fermented Allium victorialis L. extract. Korean J. Plant Res. 24: 30-39 (2011) crossref(new window)

13.
Kim SM, Kim DY, Park HR, Seo JH, Yeom BM, Jin YJ, Pyo YH. Screening the antioxidant components and antioxidant activity of extracts derived from five varieties of edible spring flowers. Korean J. Food Sci. Technol. 46: 13-18 (2014) crossref(new window)

14.
Zhang X, Lee FZ, Eun JB. Changes of phenolic compounds and pectin in Asian pear fruit during growth. Korean J. Food Sci. Technol . 39: 7-13 (2007)

15.
Hong JY, Nam HS, Kim NW, Shin SR. Changes on the components of Elaeagnus multiflora fruits during maturation. Korean J. Food Preserv. 13: 228-233 (2006)

16.
Hong JY, Nam HS, Shin SR. Changes on the antioxidant activities of extracts from the Ziziphus jujube miller fruits during maturation. Korean J. Food Preserv. 17: 712-719 (2010)

17.
Kang YJ, Yang MH, Ko WJ, Park SR, Lee BG. Studies on the major components and antioxidative properties of whole fruit powder and juice prepared from premature mandarin orange. Korean J. Food Sci. Technol. 37: 783-788 (2005)

18.
Park YG, Kim SH, Chung HG. Antioxidant potential in the fruits of Pyrus species (pear) in Korea. Korean J. Medicinal Crop Sci. 15: 335-338 (2007)

19.
Park YO, Choi JJ, Choi JH, Kim MS, Yim SH, Lee HC. Antioxidant activities of young and mature fruit in three Asian pear cultivars. Hort. Environ. Biotechnol. 30: 208-213 (2012)

20.
Yang AY, Boo HO. Phenolic compounds, antimicrobial effects and tyrosinase inhibition activities of cucumber grown greenhouse according to cultivars and growth stages. Korean J. Plant Res. 26: 645-651 (2013) crossref(new window)

21.
Maeda K, Fukuda M. Arbutin: Mechanism of its depigmenting action in human melanocyte culture. J. Pharmacol. Exp. Ther. 276: 765-769 (1996)

22.
Cui T, Nakamura K, Ma L, Li JZ, Kayahara H. Analyses of arbutin and chlorogenic acid, the major phenolic constituents in oriental pear. J. Agr. Food Chem. 53: 3882-3887 (2005) crossref(new window)

23.
Adom KK, Sorrells ME, Liu RH. Phytochemical profiles and antioxidant activity of wheat varieties. J. Agr. Food Chem. 51: 7825-7834 (2003) crossref(new window)

24.
Boo HO, Lee HH, Lee JW, Hwang SJ, Park SU. Different of total phenolics and flavonoids, radical scavenging activities and nitrite scavenging effects of Momordica charantia L. according to cultivars. Korean J. Medicinal Crop Sci. 17: 15-20 (2009)

25.
Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Bio. Med. 20: 933-956 (1996) crossref(new window)

26.
Yamakoshi J, Otsuka F, Sano A, Tokutake S, Saito M, Kikuchi M, Kubota Y. Lightening effect on ultraviolet-induced pigmentation of guinea pig skin by oral administration of a proanthocyanidin-rich extract from grape seeds. Pigm. Cell Res. 16: 629-638 (2003) crossref(new window)

27.
Hwang YS, Chun JP, Lee JC, Seo JH. Storage response of 'kamchun' and 'chuhwang' pears by harvest dates. Hort. Environ. Biotechnol. 19: 48-53 (2001)

28.
Kim DH, Moon YS, Park TS, Hwang JY, Son JH. Potent whitening activity of Aruncus dioicus extract in B16F10 melanoma cell by suppression of melanin biosynthesis. Hort. Environ. Biotechnol. 31: 813-820 (2013)

29.
Choi EO, Kim HS, Han MH, Choi YH, Park C, Kim BW, Hwang HJ. Effects of Hizikia fusiforme fractions on melanin synthesis in B16F10 melanoma cells. J. Life Sci. 23: 1495-1500 (2013) crossref(new window)

30.
Iwata M, Corn T, Iwata S, Everett MA, Fuller BB. The relationship between tyrosinase activity and skin color in human foreskins. J. Invest. Dermatol. 95: 9-15 (1990) crossref(new window)

31.
Kim JS, Seo YC, Choi WY, Kim HS, kim BH, Shin DH, Yoon CS, Lim HW, Ahn JH, Lee HY. Enhancement of antioxidant activities and whitening effect of Acer mono sap through nano encapsulation processes. Korean J. Med. Crop. Sci. 19: 191-197 (2011) crossref(new window)

32.
Jeon MH, Kim MH, Jang HJ, Lee SW, Kim JH, Kim HS, Lee SH. Whitening effect of Hizikia fusiformis ethanol extract and its fractions. J. Life Sci. 22: 889-896 (2012) crossref(new window)