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Comparison of Biological Activities of Ethanol Extracts of Unripe Fruit of Bitter Melon (Momordica charantia L.) Cultivated in Hamyang, Korea
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 Title & Authors
Comparison of Biological Activities of Ethanol Extracts of Unripe Fruit of Bitter Melon (Momordica charantia L.) Cultivated in Hamyang, Korea
Moon, Jeong-Han; Choi, Dong-Won; Kim, Seong-Eun; Seomoon, Ji-Hoon; Hong, Su-Young; Kim, Hyun-Kyu; Cho, Kye-Man; Song, Jin; Kang, Sang-Soo; Kim, Kang-Hwa; Kwon, Oh-Kyung;
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To develop health-functional food ingredients for improvement of diabetes, we examined biological activities, including total contents of polyphenols and flavonoids, antioxidant activity, and inhibition of -glucosidase and pancreatic lipase activities of ethanol extracts from unripe fruit of Momordica charantia L. cultivated in Hamyang, Korea. Ethanol extracts were tested using different ethanol concentrations (0%, 30%, 50%, and 70%) and temperatures ( and ). Experimental results showed that total polyphenol and flavonoid contents were achieved concentrations of 7.77 mg/g (tannic acid), 7.66 mg/g (gallic acid), and 10.66 mg/g (rutin). The hydroxyl radical scavenging, ABTS cation radical scavenging, and FRAP activities were 82.19%, 42.82%, and 0.19 under the same conditions, respectively. The highest inhibitory activities of -glucosidase and pancreatic lipase were achieved in the 70% ethanol extract at . These results will be useful for development of health functional foods for anti-diabetes using 70% ethanol extract from unripe fruit of bitter melon.
Momordica charantia L.;ethanol extract;-glucosidase;pancreatic lipase;antioxidant;
 Cited by
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