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Comparison of Anti-Adipogenesis Activity by Several Grape Extracts
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 1,  2011, pp.119-123
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.1.119
 Title & Authors
Comparison of Anti-Adipogenesis Activity by Several Grape Extracts
Lee, Si-Rim; Park, Chul-Hong; Kuan, Eun-Young; Lu, Yan-Qing; Kim, Hong; Kim, Ki-Chan; Son, Hyeong-U; Lee, Hyun-Jin; Heo, Jin-Chul; Lee, Sang-Han;
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 Abstract
In order to compare what kinds of transcription factors are associated with the inhibition of preadipocyte cell proliferation, we prepared several grape extracts and tested the expression patterns by reverse transcription-polymerase chain reaction. As a result, 50% ethanol extract of Campbell early seed inhibited adipogenesis derived from the MDI solution. Extract of Campbell early seed was significantly inhibited lipid droplet formation and expression of molecular factors C/EBP-alpha and delta in 3T3-L1 cells. It is suggested that grape extracts of fractions would be a good candidate for the development of regional skin fat modulator.
 Keywords
grape extracts;anti-adipogenesis;biomarkers;C/EBP transcription factor;
 Language
Korean
 Cited by
1.
삼백초 추출물의 3T3-L1 세포에 대한 지방축적 억제효과,신옥수;신연호;이강혁;김건용;김기호;박정극;안재일;송계용;

KSBB Journal, 2012. vol.27. 6, pp.381-386 crossref(new window)
1.
Inhibition of Adipogenesis in 3T3-L1 Adipocytes with Ethanol Extracts of Saururus chinensis, KSBB Journal, 2012, 27, 6, 381  crossref(new windwow)
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