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Comparison of Anti-Adipogenesis Activity by Several Grape Extracts
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 1,  2011, pp.119-123
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.1.119
 Title & Authors
Comparison of Anti-Adipogenesis Activity by Several Grape Extracts
Lee, Si-Rim; Park, Chul-Hong; Kuan, Eun-Young; Lu, Yan-Qing; Kim, Hong; Kim, Ki-Chan; Son, Hyeong-U; Lee, Hyun-Jin; Heo, Jin-Chul; Lee, Sang-Han;
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In order to compare what kinds of transcription factors are associated with the inhibition of preadipocyte cell proliferation, we prepared several grape extracts and tested the expression patterns by reverse transcription-polymerase chain reaction. As a result, 50% ethanol extract of Campbell early seed inhibited adipogenesis derived from the MDI solution. Extract of Campbell early seed was significantly inhibited lipid droplet formation and expression of molecular factors C/EBP-alpha and delta in 3T3-L1 cells. It is suggested that grape extracts of fractions would be a good candidate for the development of regional skin fat modulator.
grape extracts;anti-adipogenesis;biomarkers;C/EBP transcription factor;
 Cited by
삼백초 추출물의 3T3-L1 세포에 대한 지방축적 억제효과,신옥수;신연호;이강혁;김건용;김기호;박정극;안재일;송계용;

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