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Neuronal Cell Protection and Antioxidant Activities of Hot Water Extract from Commercial Buckwheat Tea
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 3,  2011, pp.358-365
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.3.358
 Title & Authors
Neuronal Cell Protection and Antioxidant Activities of Hot Water Extract from Commercial Buckwheat Tea
Jeong, Chang-Ho; Jeong, Hee-Rok; Choi, Sung-Gil; Shim, Ki-Hwan; Heo, Ho-Jin;
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The antioxidant and neuronal cell-protective effects of hot water extract from commercial buckwheat tea (CBTE) were evaluated. The 2,2'-azino-bis(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and malondialdehyde (MDA) inhibitory effect of the CBTE increased in a dose-dependent manner. The Intracellular reactive oxygen species (ROS) accumulation that resulted from hydrogen peroxide () treatment more significantly decreased when CBTE was present in the media than when the PC12 cells were treated only with . In the neuronal cell viability assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT), the aqueous extracts showed a protective effect against -induced neurotoxicity, and the lactate dehydrogenase (LDH) release into the medium was also inhibited by CBTE. The total phenolics of CBTE was 9,608.10 mg/100 g, and the major phenolic compounds were rutin (13.42 mg/100 g) and quercitrin (0.90 mg/100 g). These data suggested that CBTE, including the aforementioned phenolics, may be useful in reducing the risk of neurodegenerative disease.
Commercial buckwheat tea;rutin;antioxidant;neuronal cell protection;
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