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Neuronal Cell Protection and Antioxidant Activities of Hot Water Extract from Commercial Buckwheat Tea
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 3,  2011, pp.358-365
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.3.358
 Title & Authors
Neuronal Cell Protection and Antioxidant Activities of Hot Water Extract from Commercial Buckwheat Tea
Jeong, Chang-Ho; Jeong, Hee-Rok; Choi, Sung-Gil; Shim, Ki-Hwan; Heo, Ho-Jin;
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 Abstract
The antioxidant and neuronal cell-protective effects of hot water extract from commercial buckwheat tea (CBTE) were evaluated. The 2,2'-azino-bis(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and malondialdehyde (MDA) inhibitory effect of the CBTE increased in a dose-dependent manner. The Intracellular reactive oxygen species (ROS) accumulation that resulted from hydrogen peroxide () treatment more significantly decreased when CBTE was present in the media than when the PC12 cells were treated only with . In the neuronal cell viability assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT), the aqueous extracts showed a protective effect against -induced neurotoxicity, and the lactate dehydrogenase (LDH) release into the medium was also inhibited by CBTE. The total phenolics of CBTE was 9,608.10 mg/100 g, and the major phenolic compounds were rutin (13.42 mg/100 g) and quercitrin (0.90 mg/100 g). These data suggested that CBTE, including the aforementioned phenolics, may be useful in reducing the risk of neurodegenerative disease.
 Keywords
Commercial buckwheat tea;rutin;antioxidant;neuronal cell protection;
 Language
Korean
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 References
1.
Yoon MY, Kim JY, Hwang JH, Cha MR, Lee MR, Jo KJ, Park HR (2007) Protective effect of methanolic extracts from Dendrobium nobile Lindle. on $H_{2}O_{2}$-induced neurotoxicity in PC12 cells. J Korean Soc Apple Biol Chem, 50, 63-67

2.
Sagara Y, Dargusch R, Chambers D, Davis J, Schubert D, Mater P (1998) Cellular mechanisms of resistance to chronic oxidative stress. Free Radic Biol Med, 24, 1375-1389 crossref(new window)

3.
Lee YS (2007) Antioxidative and physiological activity of extracts of Angelica dahurica leaves. Korean J Food Preserv, 14, 78-86

4.
Kim DJ, Seong KS, Kim DW, Ko SR, Chang CC (2004) Antioxidative effects of red ginseng saponins on paraquat-induced oxidative stress. J Ginseng Res, 28, 5-10 crossref(new window)

5.
Ames BN (1983) Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science, 221, 1256-1264 crossref(new window)

6.
Ames BN, Shigenaga MK, Hagen TM (1993) Oxidant, antioxidants, and the degenerative disease of aging. Proc Natl Acad Sci, USA, 90, 7915-7922 crossref(new window)

7.
Heo HJ, Choi SJ, Choi SG, Shin DH, Lee JM, Lee CY (2008) Effects of banana, orange, and apple on oxidative stress-induced neurotoxicity in PC12 Cells. J Food Sci, 73, 28-32 crossref(new window)

8.
Eum HS, Kang EB, Lim YH, Lee JR, Cho IH, Kim YS, Chae KR, Hwang DY, Kwak YS, Oh YS, Cho JY (2008) The effect of exercise training on A$\beta$-42, BDNF, GLUT-1 and HSP-70 proteins in a NSE/ APPsw- transgenic model for Alzheimer's disease. J Life Sci, 18, 796-803 crossref(new window)

9.
Yoon MY, Lee BB, Kim JY, Kim YS, Park EJ, Lee SC, Park HR (2007) Antioxidant activity and neuroprotective effect of Psoralea corylifolia Linne Extracts. Kor J Pharmacogn, 38, 84-89

10.
Kim YS, Chung SH, Suh HJ (1994) Rutin and mineral contents on improved kinds of Korean buckwheat at growing stage. Korean J Food Sci Technol, 26, 759-763

11.
Yeshajahu P, George SR (1972) Amino acid composition of buckwheat. J Agric Food Chem, 20, 270-274 crossref(new window)

12.
Havsteen B (1983) Flavonoids a class of natural products of high pharmaco-logical potency. Biochem Pharm, 32, 1141-1148 crossref(new window)

13.
Lee JS, Son HS, Maeng YS, Chang YK, Ju JS (1994) Effects of buchwheat on organ weight, glucose and lipid metabolism in streptozotocin-induced diabetic rats. Korean J Nutr, 27, 819-827

14.
Choi SN, Chung NY (2007) The quality characteristics of bread with added buckwheat powder. Korean J Food Cookery Sci, 23, 664-670

15.
Lee JS, Lee MH, Son HS, Mang YS (1996) Effects of buchwheat on the activities of pancreatic digestive enzymes in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr, 25, 831-838

16.
Zhang M, Chen H, Li J, Pei Y, Liang Y (2010) Antioxidant properties of tartary buckwheat extracts as affected by different thermal processing methods. LWT-Food Sci Technol, 43, 181-185 crossref(new window)

17.
Li CH, Matsui T, Matsumoto K, Yamasaki R, Kawasaki T (2002) Latent production of angiotensin I-converting enzyme inhibitors from buckwheat protein. Journal of Peptide Science, 8, 267-274 crossref(new window)

18.
Wei C, Wei-Jun C, Zhi-Rong S, Ya-Ping Y (2008) Protective effects of ethanolic extracts of buckwheat groats on DNA damage caused by hydroxyl radicals. Food Research International, 41, 924-929 crossref(new window)

19.
Hwang EJ, Lee SY, Kwon SJ, Park MH, Boo HO (2006) Antioxidative, antimicrobial and cytotoxic activities of Fagopyrum esculentum Möench extract in germinated seeds. Korean J Medicinal Crop Sci, 14, 1-7

20.
Kwak CS, Lim SJ, Kim SA, Park SC, Lee MS (2004) Antioxidative and antimutagenic effects of Korean buchwheat, sorghum, millet and job's tears. J Korean Soc Food Sci Nutr, 33, 921-929 crossref(new window)

21.
Suh HJ, Chung SH, Kim YS, Lee SD (1997) Free radical scavenging activities and inhibitory effects on xanthine oxidase of buckwheat(Suwon No 5). J Korean Soc Food Sci Nutr, 26, 411-416

22.
Lee MH, Lee JS, Yang HC (2008) $\alpha$-amylase inhibitory activity of flower and leaf extracts from buckwheat (Fagopyrum esculentum). J Korean Soc Food Sci Nutr, 37, 42-47 crossref(new window)

23.
Lee YS, Lee JH (2006) Screening of active substance FS11052 as an inhibitor of neurotransmitter release from PC12 cells. Korean J Vet Res, 46, 87-96

24.
Kim DO, Jeong SW, Lee CY (2003) Antioxidant capacity of phenolic phytochemical from various cultivars of plums. Food Chem, 81, 321-326 crossref(new window)

25.
Pellegrin N, Re R, Yang M, Rice-Evans C (1998) Screening of dietary carotenoids and carotenoid-rich fruit extracts for antioxidant activities applying 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) radical cation decolorization assay. Method Enzymol, 299, 379-389

26.
Benzie IFF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Anal Biochem, 239, 70-76 crossref(new window)

27.
Chang ST, Wu JH, Wang SY, Kang PL, Yang NS, Shyur LF (2001). Antioxidant activity of extracts from Acacia confusa bark and heartwood. J Agric Food Chem, 49, 3420-3424 crossref(new window)

28.
Heo HJ, Cho HY, Hong BS, Kim EK, Kim BK, Shin DH (2001) Protective effect of 4',5-dihydroxy-3', 6,7-trimethoxyflavone from Artemisia asiatica against A$\beta$-induced oxidative stress in PC12 cells. Amyloid, 8, 194-201 crossref(new window)

29.
Jeong CH, Choi SG, Heo HJ (2008) Analysis of nutritional components and evaluation of functional activities of Sasa borealis leaf tea. Korean J Food Sci Technol, 40, 586-592

30.
Maeng YS, Park HK, Kwon TB (1990) Analysis of rutin contents in buckwheat and buckwheat food. Korean J Food Sci Technol, 22, 732-737

31.
Ya-ping Y, Cheng-rui T, Wei C (2008) Anti-oxidative constituents of ethanol extract from buckwheat seeds by HPLC-electro-spray MS. Agricultural Sciences in China, 7, 356-362 crossref(new window)

32.
Tang CH, Peng J, Zhen DW, Chen Z (2009) Physicochemical and antioxidant properties buckwheat (Fagopyrum esculentum Moench) protein hydrolysates. Food Chem, 115, 672-678 crossref(new window)

33.
Osawa T (1994) Novel natural antioxidant for utilization in food and biological system. pp. 241-251. In : Postharvest biochemistry of plant food-material in the tropics. Uritani I, Garcia VV, Mendoza EM (ed). Japan Scientific Societies Press, Tokyo, Japan

34.
Uchida K, Stadtman ER (1993) Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenese. A possible involvement of intra and intermolecular cross-linking reaction. J Biol Chem, 268, 6388-6393

35.
Colditz GA, Branch LG, Lipnick RJ, Willett WC, Rosner B, Posner BM, Hennekens CH (1985) Increased green and yellow vegetable intake and lowered cancer deaths in an elderly population. Am J Clin Nutr, 41, 32-36

36.
Choi SJ, Yoon KY, Choi SG, Kim DO, Oh SJ, Jun WJ, Shin DH, Cho SH, Heo HJ (2007) Protective effect of Acanthopanax senticosus on oxidative stress induced PC12 cell death. Food Sci Biotechnol, 16, 1035-1040

37.
Jeong CH, Kwak JH, Kim JH, Choi GN, Jeong HR, Heo HJ (2010) Neuronal cell protective effects of methanol extract from Cheonggukjang using in vitro system. Korean J Food Sci Technol, 42, 768-772

38.
Jeong CH, Kwak JH, Kim JH, Choi GN, Kim DO, Heo HJ (2010) Neuronal cell protective and antioxidant effects of phenolics obtained from Zanthoxylum piperitum leaf using in vitro model system. Food Chem, 125, 417-422