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Effects of Plantago asiatica L. on antioxidative activities and lipid levels in hyperlipidemic Sprague-Dawley(SD) rats
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 3,  2011, pp.383-389
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.3.383
 Title & Authors
Effects of Plantago asiatica L. on antioxidative activities and lipid levels in hyperlipidemic Sprague-Dawley(SD) rats
Park, Sung-Jin; Kim, Na-Young; Kim, Cheun-An;
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This study was carried out to investigate the effects of Plantago asiatica L. extract on anti oxidative potential, free radical generation and the lipid levels in rats. Sprague-Dawley(SD) rats were divided into two groups based on their diet, as follows: the AIN-76 diet (control group), and the modified AIN-76 diet(cholesterol 0.5%) with 0.5% P. asiatica extract, for 7 weeks. The body weight and teed efficiency ratios of the two groups did not significantly differ. The antioxidative potentials more significantly increased in the group that was fed P. asiatica extract than in the control group(p<0.05). There was no difference in the rate of free radical generation, though. The weights of the organs, such as heart, kidney, liver, and spleen, of the rats in the two groups did not differ, though. The ratio of the HDL cholesterol to the total cholesterol in the P. asiatica group was significantly higher than that in the control group, and the other serum lipid parameters (total cholesterol, HDL cholesterol, triglyceride, and phospholipids) did not differ between the two groups. These results imply that supplementation with P. asiatica extract may improve the antioxidant potential and decrease the lipid levels in the blood.
P. asiatica;total cholesterol;HDL-cholesterol;triglyceride;antioxidative activities;
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