Advanced SearchSearch Tips
In vitro Antioxidant Activity of the Aqueous of Angelicae gigas Nakai Leaves
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 6,  2011, pp.817-823
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.6.817
 Title & Authors
In vitro Antioxidant Activity of the Aqueous of Angelicae gigas Nakai Leaves
Park, Sung-Jin; Yoon, Jung-Han; Kim, Young-Eon; Yoon, Won-Byong; Kim, Jong-Dai;
  PDF(new window)
Angelicae gigas Nakai has been used as a traditional medicine as well as an edible vegetable in South Korea. In this study, the total phenolic and flavonoid content and antioxidants of A. gigas Nakai leaves were examined in vitro via hydroxyl-radical-scavenging activity, reducing power activity, metal chelating assay, and DPPH-free -radical-scavenging assay. Among all the extracts from A. gigas Nakai leaves, the ethanol extract showed the strongest effects in all of the assays. The values for the DPPH-radical-scavenging activities of ethanol, methanol, and water extracts were 31.47, 42.14, and , respectively. Among the extracts from A. gigas Kakai leaves, the ethanol extract had the highest levels of total phenolics ( mg TAN/g) and total flavonoids ( mg QE/g), which correlated strongly with the individual phenolic-compound (p-hydroxybenzoic acid, vanillin, and trans-ferulic acid) contents. The ethanol extract also showed stronger antioxidant activity than tocopherol in hydroxyl- radical-scavenging activity assay. These results indicate that the ethanol extract of A. gigas Kakai leaves possesses significant antioxidant properties, which suggests its great potential as a functional-food ingredient in the food industry.
Angelicae gigas Nakai leaf;antioxidant;total phenolics;total flavonoids;phenolic acids;
 Cited by
당귀의 재배 및 유통과정 중 생물적 위해요소 분석,박경훈;김병석;이정주;윤혜정;김세리;김원일;윤종철;류경열;

한국토양비료학회지, 2012. vol.45. 6, pp.1216-1221 crossref(new window)
Biological Hazard Analysis of Angelica gigas Nakai on Production and Marketing Steps, Korean Journal of Soil Science and Fertilizer, 2012, 45, 6, 1216  crossref(new windwow)
Occurrence of Weed Flora and Their Yield Loss in Angelica gigas Upland Fields of Minor Crop in Korea, Weed & Turfgrass Science, 2016, 5, 2, 65  crossref(new windwow)
Anti-Photoaging Effects of Angelica acutiloba Root Ethanol Extract in Human Dermal Fibroblasts, Toxicological Research, 2017, 33, 2, 125  crossref(new windwow)
Ames BN, Shigenaga MK, Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci, USA, 90, 7915-7922 crossref(new window)

Halliwell B, Gutteridge JMC, (1990) Role of free radicals and catalytic metal ions in human disease; an overview. Method Enzymol, 186, 1-85 crossref(new window)

Collin AR (1999) Oxidative DAN damage, antioxidants, and cancer. Bioessays 21, 238-246 crossref(new window)

Hertog MGL, Feskens EJM, Hollman PEH, Katanm MB, Kromhout D (1993) Dietary antioxidant flavonoids and risk of coronary heart-diseases the Zutphen elderly study. Lancet 342, 1007-1011 crossref(new window)

Jaghav SJ, Nimbalkar SS, Kulkarni AD, Madhavi DL (1996) Lipid oxidation in biological and food systems. In D, L. Madhavi, S. S.; Deshpande, ; D. K. Salunkhe (Eds.), Food antioxidants, pp 5-63 Dekker Press: New York

Mariod AA, Matthaus B, Hussein IH (2008) Antioxidant properties of methanolic extracts from different parts of Sclerocarya birrea. Int J Food Sci Technol, 43, 921-926 crossref(new window)

Liyana‐Pathirana CM, Shahidi F (2006) Importance of insoluble bound phenolics to antioxidant properties of wheat. J Agric Food Chem, 54, 1256-1264 crossref(new window)

Mariod AA, Matthaus B, Eichner K, Hussein IH (2006) Antioxidant activity of extracts from Sclerocarya birrea kernel oil cake. Grasas Aceites 57, 361-366

Williams GM, Iatropoulos MJ, Whysner J (1999) Safety assessment to butylated hydroxyanisol and butylated hydroxytoluene as antioxidant food additives. Food Chem Toxicol, 37, 1027-1038 crossref(new window)

Moure A, Franco D, Sineiro J, Dominguez H, Nunez MJ, Lema JM (2000) Evaluation of extracts from Gevuina hulls as antioxidants. J Agric Food Chem, 48, 3890-3897 crossref(new window)

Shao HB, Chu LY, Lu ZH, Kang CM (2008) Primary antioxidant free radical scavenging and redox signaling pathways in higher plant cells. Int J Biol Sci, 4, 8-14

Reiter R, Tang L, Garcia JJ, Munoz-Hoyos A (1997) Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci, 60, 2255-2271 crossref(new window)

Thomson MJ (1995) The role of free radicals and antioxidants: how do we know that they are working? Criti Rev Food Sci Nutr, 35, 21-39 crossref(new window)

Wessler S, Kleiger RE, Cornfield J, Teitelbaum SL (1974) Coumarin theraphy in acute myocardial infarction. A Hobson's choice Arch Intern Med, 134, 774-779 crossref(new window)

Yoon HR, Yook CS (1995) Studies on the constituents of Angelica gigas Nakai. Bull Kyung Hee Pharma Sci, 23, 55-71

Ryu KS, Hong ND, Kim NJ, Kong YY (1990) Studies on the coumarin constituents of the root of Agelica gigas Nakai. Isolation of decursinol angelate and assay of decursinol angelate and decursin. Korean J Pharmacognosy, 21, 64-68

Park CS, Kim ML (2006) Functional properties of Angelica gigas Nakai leave (AGL) extracts and quality characteristics of Mumalangi Kimchi added AGL. Korean J Food Cookery Sci, 23, 728-735

Singleton VL, Rossi JA (1965) Colorimetry of total phenolics with phosphomolybdic -phosphotungstic acid reagents. Am J Enol Vitricul, 16, 144-158

Moreno MIN, Isla MI, Sampietro AR, Vattuone MA (2000) Comparison of the free radical-scavenging activity of propolis from several regions of Argentina. J Ethnopharmacol, 71, 109-114 crossref(new window)

Shimada K, Fujikawa K, Yahara K, Nakamura T (1992) Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion. J Agric Food Chem, 40, 945-948 crossref(new window)

Oyaizu M (1986) Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine. Jpn J Nutr, 44, 307-315 crossref(new window)

Halliwell B, Gutteridge JMC (1981) Formation of a thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts: the role of superoxide and hydroxyl radicals. FEBS Lett, 128, 347-352 crossref(new window)

Que F, Mao L, Zhu C, Xie G (2006) Antioxidant properties of Chinese yellow wine, its concentrate and volatiles. LWT-Food Sci. Technol. 39, 111-117 crossref(new window)

Waldron KW, Parr AJ, Ng A, Ralph J (1996) Cell wall esterified phenolic dimers: identification and quantification by reverse phase high performance liquid chromatography and diode array detection. Phytochem Anal, 7, 305-312 crossref(new window)

Lim YY, Murtijaya J (2007) Antioxidant properties of Phyllanthus amarus extracts as affected by different drying methods. LWT‐Food Sci Technol, 40, 1664-1669 crossref(new window)

Chen FA, Wu AB, Shieh P, Kuo DH, Hsieh CY (2006) Evaluation of the antioxidant activity of Ruellia tuberose. Food Chem, 94, 14-18 crossref(new window)

Leong LP, Shui G (2002) An investigation of antioxidant capacity of fruits in Singapore markets. Food Chem, 76, 69-75 crossref(new window)

Zheng W, Wang SY (2001) Antioxidant activity and phenolic compounds in selected herbs. J Agric Food Chem, 49, 5156-5170 crossref(new window)

Meir S, Kanner J, Akiri B, Philosoph‐Hadas S (1995) Determination and involvement of aqueous reducing compounds in oxidative defense systems of various senescing leaves. J Agric Food Chem, 43, 1813-1819 crossref(new window)

Kosar M, Dorman HJD, Hiltunen R (2005) Effect of an acid treatment on the phytochemical and antioxidant characteristics of extracts from selected Lamiaceae species. Food Chem, 91, 525-533 crossref(new window)

Povirk LF (1996) DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutat Res, 355, 71-89 crossref(new window)

Girotti AW (1998) Lipid hydroperoxide generation, turnover, and effector action in biological systems. J Lipd Res, 39, 1529-1542

Wang J, Yuan X, Jin Z, Tian Y, Song H (2007) Free radical and reactive oxygen species scavenging activities of peanut skins extract. Food Chem, 104, 242-250 crossref(new window)

Edlin DAN, Narbad A, Gasson MJ, Dickinson JR, Lloyd D (1998) Purification and characterization of hydroxycinnamate decarboxylase from Brettanomyces anomalus. Enzyme Microb Tech, 22, 232-239 crossref(new window)