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Hypoglycemic Effects of a Medicinal Herb Mixture Prepared through the Traditional Antidiabetic Prescription
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 6,  2011, pp.923-929
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.6.923
 Title & Authors
Hypoglycemic Effects of a Medicinal Herb Mixture Prepared through the Traditional Antidiabetic Prescription
Kim, Jung-Ok; Lee, Gee-Dong;
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 Abstract
For the purpose of investigating the in vitro antidiabetic activity of a medicinal herb mixture prepared through traditional antidiabetic prescription, the study analyzed the existence of insulin-similar components and examined -amylase and -glucosidase inhibition activity. As a result of arranging the medicinal herb mixture extracts over the 3T3-L1 fibroblast in the concentration of , which confirmed that it included much of insulin sensitizer components as 151.7% in the differentiation of 3T3-L1 fibroblast. The inhibition activity against -amylase of the medicinal herb mixture extracts as hypoglycemic agent were 38.4, 31.5 and 16.6% in the concentration of 10.0, 1.0 and 0.1 mg/mL, respectively. The inhibition activity against -glucosidase of the medicinal herb mixture extracts were 81.3, 35.8 and 26.7% in the concentration of 10.0, 1.0 and 0.1 mg/mL, respectively. The inhibition activity against -glucosidase in the ethyl acetate fractions of the water and 80% ethanol extracts were 66.9% and 55.1%, respectively, the highest levels in the various solvent extracts.
 Keywords
medicinal herb mixture;hypoglycemic effects;-amylaseinhibition activity;-glucosidase inhibition activity;insulin-similar components;
 Language
Korean
 Cited by
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