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Inhibitory Effect of Angelica keiskei Extracts on Melanogenesis
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 6,  2011, pp.998-1001
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.6.998
 Title & Authors
Inhibitory Effect of Angelica keiskei Extracts on Melanogenesis
Son, Hyeong-U; Nam, Dong-Yoon; Kim, Min-Ah; Cha, Yong-Su; Kim, Jong-Myung; Shin, Yong-Kyu; Lee, Sang-Han;
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 Abstract
Angelica keiskei is a perennial herb belonging to the Umbelliferae family. In this study, the whitening effect of A. keiskei extracts was examined through melanogenesis and tyrosinase inhibitory assays. The ethanol extract (50%) significantly inhibited tyrosinase in a concentration-dependent manner. RT-PCR revealed that the extract exhibited decreased expression of tyrosinase, tyrosinase-related protein-1, tyrosinase-related protein-2, and melanocyte-inducing transcription factor. These results suggest that the extract can be used as an ingredient for the development of cosmeceuticals.
 Keywords
Angelica keiskei;melanogenesis;tyrosinase;B16F10;
 Language
Korean
 Cited by
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 References
1.
Yoon NY, Eom TK, Kim MM, Kim SK (2009) Inhibitory effect of phlorotannins isolated from Ecklonia cava on mushroom tyrosinase activity and melanin formation in mouse B16F10 melanoma cells. J Agric Food Chem, 57, 4124-4129 crossref(new window)

2.
Masaru M, Fumihide M, Masayuki F (2009) Regulation of melanin synthesis by the TGF-$\beta$ family in B16 melanoma cells. Mol Biol Rep, 36, 1247-1250 crossref(new window)

3.
Lee BC, Sim GS, Kim JH, Kim KH, Lee HJ, Pyo HB (2006) Synthesis of 2',4'-dimethoxyflavone and its anti-pigmentation effect. J Soc Cosmet Scientists Korea, 32, 153-160

4.
Kwak YJ, Kim KS, Kim KM, Yu HY, Chung E, Kim SJ, Cha JY, Lee YC, Lee JH (2011) Fermented Viola mandshurica inhibits melanogenesis in B16 melanoma cells. Biosci Biotechnol Biochem, 75, 841-847 crossref(new window)

5.
Jung HK. Park PS, Huh NC, Kim SO, Kim KS, Lee MY (1998) Inhibitory effect of Angelica keiskei Koidz green juice on the liver damage in CCL4-treated rats. J Korean Soc Food Sci Nutr, 27, 531-536

6.
Tatsuji E, Hiromu O, Kinuko N, Yoko K, Katsumi S, Masashige T, Eiji K, Hiroaki S, Ikunoshin K (2007) Antidiabetic activities of chalcones isolated from a Japanese herbm Angelica keiskei. J Agric Food Chem, 55, 6013-6017 crossref(new window)

7.
Kim SJ, Cho JY, Wee JH, Jang MY, Rim YS, Kim C, Shin SC, Moon JH, Park KH (2005) Isolation and identification of two psoralen derivatives as antioxidative compounds from the aerial parts of Angelica keiskei. Korean J Food Sci Technol, 37, 656-659

8.
Jeong SI, Han WS (1999) Germanium(IV) content in the Korean Angelica keiskei Koidz. Korean J Medicinal Crop Sci, 7, 11-15

9.
Jo HW, Park JC (2008) Phenolic compounds isolated from the leaves of Angelica keiskei showing DPPH radical scavenging effect. Kor J Pharmacogn, 39, 146-149

10.
Hiroshi O, Rei N, Kimiye B (2005) Beneficial effect of laserpitin, a coumarin compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol, 32, 1104-1109 crossref(new window)

11.
Park JY, Jeong HJ, Kim YM, Park SJ, Rho MC, Park KH, Ryu YB, Lee WS (2011) Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition. Bioorg Med Chem Lett, 21, 5602-5604 crossref(new window)

12.
Toshihiro A, Jarukuni T, Daisuke H, Motohiko U, Yumiko K, Fumio E, Takashi S, Hoyoku N (2006) Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. J Nat Prod, 69, 38-42 crossref(new window)

13.
Website of Korea Statistics Administration, http://www.kostat.go.kr/

14.
Kim KH, Ko KI, Kang EJ, Yang EK, Park SN (2004) A research trend of natural product on well-being industry. J Soc Cosmet Scientist Korea, 30, 329-343

15.
Jun YS, Rhee SH, Takako Y, Chung HY (1999) Inhibition of tyrosinase by green tea components. Life Sci, 65, 241-246

16.
Heo JC, Rho JR, Kim TH, Kim SY, Lee SH (2008) An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers. Int J Mol Med, 22, 763-767

17.
Julapalli VR, Graham DY (2005) Appropriate use of intravenous proton pump inhibitors in the management of bleeding peptic ulcer. Dig Dis Sci, 50, 1185-1193 crossref(new window)

18.
An SM, Park CH, Heo JC, Park JY, Woo SW, Seo JH, Lee MS, Cho KH, Shin HM, Lee SH (2007) Gastrodia elata blume protects against stress-induced gastric mucosal lesions in mice. Int J Mol Med, 20, 209-215