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Inhibitory Effect of Angelica keiskei Extracts on Melanogenesis
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  • Journal title : Korean Journal of Food Preservation
  • Volume 18, Issue 6,  2011, pp.998-1001
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2011.18.6.998
 Title & Authors
Inhibitory Effect of Angelica keiskei Extracts on Melanogenesis
Son, Hyeong-U; Nam, Dong-Yoon; Kim, Min-Ah; Cha, Yong-Su; Kim, Jong-Myung; Shin, Yong-Kyu; Lee, Sang-Han;
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Angelica keiskei is a perennial herb belonging to the Umbelliferae family. In this study, the whitening effect of A. keiskei extracts was examined through melanogenesis and tyrosinase inhibitory assays. The ethanol extract (50%) significantly inhibited tyrosinase in a concentration-dependent manner. RT-PCR revealed that the extract exhibited decreased expression of tyrosinase, tyrosinase-related protein-1, tyrosinase-related protein-2, and melanocyte-inducing transcription factor. These results suggest that the extract can be used as an ingredient for the development of cosmeceuticals.
Angelica keiskei;melanogenesis;tyrosinase;B16F10;
 Cited by
신선초 추출물의 아토피 억제활성,김민아;손형우;남동윤;차용수;신용규;최용희;이상한;

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