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Anti-oxidant and Anti-skin-aging Effects of Abalone Viscera Extracts in Human Dermal Fibroblasts
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  • Journal title : Korean Journal of Food Preservation
  • Volume 19, Issue 4,  2012, pp.463-469
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2012.19.4.463
 Title & Authors
Anti-oxidant and Anti-skin-aging Effects of Abalone Viscera Extracts in Human Dermal Fibroblasts
Li, Jinglei; Tong, Tao; Ko, Du-Ock; Chung, Dong-Ok; Jeong, Won-Chul; Kim, Ji-Eun; Kang, Seong-Gook;
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In this study, the anti-oxidant and anti-elastase activities of four abalone viscera extracts were investigated to screen the most promising extract. This extract was further studied in terms of its anti-skin-aging properties. In the DPPH-scavenging assay, the Tris-HCl extract showed a radical-scavenging activity, which was followed closely by the ethanol extract that had a scavenging activity. In the anti-elastase assay, however, the ethanol extract showed the significantly highest elastase inhibition activity. Furthermore, none of the extracts had a harmful effect on the human dermal fibroblast, as revealed in the MTT assay. In the cell study, the effect of the ethanol extract at various concentrations on the human dermal fibroblast was investigated. At the 10 concentration, the ethanol extract boosted the pro-collagen type I synthesis to ng/mL and reduced the MMP-1 to ng/mL, which was considered the optimum concentration. This is the first study that focused on the anti-oxidant and anti-skin-aging effects of abalone viscera extract. Its results may provide fundamental data for further study.
 Cited by
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Puizina-Ivi N (2008) Skin ageing. Acta Dermatoven APA, 17, 47-54

Moon HJ, Lee SR and Shim SN (2008) Fucoidan Inhibits UVB-Induced MMP-1 Expression in Human Skin Fibroblasts. Pharmaceut Soc Japan, 31, 284-289

Vayalil PK, Mitta A, Hara Y and Craig A (2004) Green Tea Polyphenols Prevent Ultraviolet Light-Induced Oxidative Damage and Matrix Metalloproteinases Expression in Mouse Skin. J Invest Dermatol, 122,1480-1487 crossref(new window)

Kim SY, Kim SJ and Lee JY (2004) Protective Effects of Dietary Soy Isoflavones against UV-Induced Skin-Ageing in Hairless Mouse Model. J Am Coll Nutr, 23, 157-162 crossref(new window)

Baumann L (2007) Skin ageing and its treatment. J Pathol, 211, 241-251 crossref(new window)

Cho HS, Lee MH, Lee JW and No KO (2007) Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. Photodermatol, 23, 155-162 crossref(new window)

Prahl S, Kueper T, Biernoth T, Wohrmann Y and Munster A (2008) Ageing skin is functionally anaerobic: Importance of coenzyme Q10 for anti ageing skin care. BioFactors, 32, 245-255 crossref(new window)

Richard A and Baxter MD (2008) Anti-ageing properties of resveratrol: review and report of a potent new antioxidant skin care formulation. J Cosmet Dermatol, 7, 2-7 crossref(new window)

Lee Y, Hong CO, Nam MH and Kim JH (2011) Antioxidant and Glycation Inhibitory Activities of Gold Kiwifruit, Actinidiachinensis. J Korean Soc Appl Biol Chem, 54, 460-467 crossref(new window)

Gonzalez M, Caride B, Lamas A and Taboada C (2001) Nutritional value of the marine invertebrates Anemoniaviridis and Haliothistuberculata and effects on serum cholesterol concentration in rats. J Nutr Biochem, 12, 512-517 crossref(new window)

Peng WD, Chen QL, Zhao JH et al (2004) Effects of enzymolytic extracts of abalone on learning and memory in mice. Acta Nutrimenta Sinica, 1, 45-48

Lee CG, Kwon HK, Ryu JH, Kang SJ et al (2010) Abalone visceral extract inhibit tumor growth andmetastasis by modulating Cox-2 levels and CD8+T cell activity. BMC Complement. Altern. Med. 10, 60 crossref(new window)

Li GY, Chen SG, Wang YM, Xue Y et al (2011) A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannaiIno: Purification, structure identification and anticoagulant activity. Int J Biol Macromol, 49, 1160-1166 crossref(new window)

Chiou TK, Lai MM and Shiau CY (2001) Seasonal variations of chemical constituents in the muscle and viscera of small abalone fed different diets. Fisheries Sci, 67, 146-156 crossref(new window)

ScharffetterKK, Brenneisen P, Wenk J, Herrmann G, Ma G and Kuhr L (2000) Photoageing of the skin from phenotype to mechanisms. Exp Gerontol, 35, 307-316 crossref(new window)

Myllyla R, Majamaa K, Gunzler K, Hanauske-Abel HM and Kivirikko KI (1984) Ascorbateis consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase. J Biol Chem, 259, 5403-5405

Wei H and Frenkel K (1993) Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters. Carcinogenesis, 14, 1195-201 crossref(new window)

Bieth JG (1986) Elastases: Catalytic and biological properties, In Biology of Extra Cellular Matrix, Vol. 1:Regulation of Matrix Accumulation. Academic Press, New York, USA, p 217-320

Steinbrecher T, Herenn A, Dormann KL, Merfort I and ALabahn (2008) Bornyl (3,4,5-trihydroxy)-cinnamate-An optimized human neutrophil elastase inhibitor designed by free energy calculations. Bioorg Med Chem Lett, 16, 2385-2390 crossref(new window)

Lee KK, Kim JH, Cho JJ and Choi JD (1999) Inhibitory effects of 150 plant extracts on elastase activity, and their anti-inflammatory effects. Int J Cosmet Sci, 21, 71-82 crossref(new window)

Xu GH, Ryoo IJ, Kim YH, Choo SJ and Yoo ID (2009) Freer radical scavenging and antielastase activities of flavonoids from the fruits of Thujaorientalis. Arch Pharm Res, 32, 275-282 crossref(new window)

Kwak YJ, Lee DH, Kim NM and Lee JS (2005) Screening and extraction condition of anti-skin ageing elastase inhibitor from medicinal plants. Korean J Medicinal Crop Sci, 13, 213-216

Roh EJ, Kim BK and Kim DS (2011) Antioxidative activity and antiageing effects of tetrapanaxpapyriferum extract. J Korean Oil Chemists' Soc, 28, 219-224

Lee HJ, Lim GN, Park MA and Park SN (2011) Antibacterial and Antioxidative Activity of Lespedeza cuneata G. Don Extracts. Korean J Microbiol Biotechnol, 39, 63-69

Varani J, Shayevitz J, Perry D, Mitra RS, Nickoloff BJ and Voorhees JJ (1990) Retinoic acid stimulation of human dermal fibroblast proliferation is dependent on suboptimal extracellular $Ca^{2+}$ concentration. Am J Pathol, 136, 1275-1281

Varani J, Mitra RS, Gibbs D, Phan SH, Dixit VM, Mitra RJ, Wang T et al (1990) All-Trans Retinoic Acid Stimulates Growth and Extracellular Matrix Production in Growth-Inhibited Cultured Human Skin Fibroblasts. J Invest Dermatol, 94, 717-723 crossref(new window)

Schwartz E, Cruickshank FA, Mezick JA, Kligman LH (1991) Topical All-Trans Retinoic Acid Stimulates Collagen Synthesis In Vivo. J Invest Dermatol, 96, 975-978 crossref(new window)

Wu NY, Ishikawa Y, Brian DN, Genge R and Wuthier RE (1997) Retinoic acid stimulates matrix calcification and initiates type I collagen synthesis in primary cultures of avian weight-bearing growth plate chondrocytes. J Cell Biochem, 65, 209-230 crossref(new window)

Woessner JF and Taplin CJ (1988) Purification and properties of a small latent matrix metalloproteinase of the rat uterus. J Biol Chem, 263, 16918-16925

Woessner JF (1991)Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J, 5, 2145-2154 crossref(new window)

Kim MS, Kim YK, Cho KH and Chung JH (2006) Regulation of type I procollagen and MMP-1 expression after single or repeated exposure to infrared radiation in human skin. Mech Ag Dev, 127, 875-882 crossref(new window)

Lahmann C, Biol D, Bergemann J, Harrison J and Young (2001) Matrixmetalloproteinase-1. Lancet, 357 (9260), 935-936 crossref(new window)