Advanced SearchSearch Tips
Evaluation of antioxidant, α-glucosidase inhibition and acetylcholinesterase inhibition activities of Allium hookeri root grown in Korea and Myanmar
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
  • Journal title : Korean Journal of Food Preservation
  • Volume 23, Issue 2,  2016, pp.239-245
  • Publisher : The Korean Society of Food Preservation
  • DOI : 10.11002/kjfp.2016.23.2.239
 Title & Authors
Evaluation of antioxidant, α-glucosidase inhibition and acetylcholinesterase inhibition activities of Allium hookeri root grown in Korea and Myanmar
Park, Joo Young; Yoon, Kyung Young;
  PDF(new window)
This study was conducted to compare the functionality (antioxidant, anti-diabetic, and anti-dementia activities) of the methanol extract of Allium hookeri root grown in Korea (KR) and Myanmar (MR). The total polyphenol and flavonoid contents of KR and MR were 5.27 and 4.80 mg GAE/g, and 0.35 and 0.24 mg QE/g, respectively. KR contained significantly higher levels of total polyphenols and total flavonoids than those of MR (p<0.05). The IC50 values of KR and MR were 6.53 and 5.31 mg/mL, respectively, for DPPH radical scavenging activity. However, KR had a significantly higher ABTS radical scavenging activity, chelating ability, and reducing power compared with those of MR (p<0.05). In the evaluation of anti-diabetic activity, KR showed significantly higher inhibition activity than acarbose and MR at whole concentrations (p<0.05). KR and MR had acetylcholinesterase inhibition activities that of 51.44% and 44.33%, respectively, at a 50 mg/mL concentration. These results suggested that roots of A. hookeri, especially KR, could be useful in improving diabetic and dementia disorders due to their high antioxidant, anti-diabetic, and anti-dementia activities.
Allium hookeri;antioxidant activity; inhibition activity;acetylcholinesterase inhibition activity;
 Cited by
Ayam VS (2011) Allium hookeri, Thw. Enum. A lesser known terrestrial perennial herb used as food and its ethnobotanical relevance in manipur. Afr J Food Agric Nutr Dev, 11, 5389-5412

Kim CH, Lee MA, Kim TW, Jang, JY, Kim, HJ (2012) Anti-inflammatory effect of Allium hookeri root methanol extract in LPS-induced RAW264.7 cells. J Korean Soc Food Sci Nutr, 41, 1645-1648 crossref(new window)

Bae GC, Bae DY (2012) The anti-inflammatory effects of ethanol extract of Allium hookeri cultivated in South Korea. Korean J Herbology, 27, 55-61

Kwon EJ, Ryu DY, Surh JH (2013) Quality characteristics of onions applied with methylsulfonylmethane (MSM) during cultivation. Korean J Food Sci Technol, 45, 213-220 crossref(new window)

Park JY, Yoon KY (2014) Comparison of the nutrient composition and quality of the root of Allium hookeri grown in Korea and Myanmar. Korean J Food Sci Technol, 46, 544-548 crossref(new window)

Oh JY, Kim WI, An CG, Kim HD, Hong KP (2014) The growth characteristics of Allium hookeri as altitudes in Gyeongnam. Korean J Hor Sci Technol, 32(sup), 79-80

Won JY, Yoo YC, Kan EJ, Yagn H, Kim GH, Seong BJ, Kim SI, Han SH, Lee SS, Lee KS (2013) Chemical components, DPPH radical scavenging activity and inhibitory effects on nitric oxide production in Allium hookeri cultivated under open field and greenhouse conditions. J Korean Soc Food Sci Nutr, 42, 1351-1356 crossref(new window)

You BR, Kim HJ (2013) Quality characteristics of Kimchi added with Allium hookeri root. J Korean Soc Food Sci Nutr, 42, 1649-1655 crossref(new window)

Folin O, Denis W (1912) On phosphotungstic-phosphomolybdic compounds as color reagents. J Biol Chem, 12, 239-243

Moreno MIN, Isla MI, Sampietro AR, Vattuone MA (2000) Comparison of the free radical-scavenging activity of propolis from several regions of Argentina. J Ethnopharmacol, 71, 109-114 crossref(new window)

Blois MS (1958) Antioxidant determinations by the use of a stable free radical. Nature, 181, 1199-1200 crossref(new window)

Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Bio Med, 26, 1231-1237 crossref(new window)

Dinis TC, Madeira VMC, Almeida LM (1994) Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys. 315, 161-169 crossref(new window)

Mau JL, Lin HC, Song SF (2002) Antioxidant properties of several specialty mushrooms. Food Res Int, 35, 519-526 crossref(new window)

Phan MAT, Wang J, Tang J, Lee YZ, Ng K (2013) Evaluation of ${\alpha}$-glucosidase inhibition potential of some flavonoids from Epimedium brevicornum. LWT-Food Sci Technol, 53, 492-498 crossref(new window)

Ellman GL, Courtney KD, Andres V, Featherstone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol, 7, 88-95 crossref(new window)

Yu MH, Im HG, Lee HJ, Ji YJ, Lee IS (2006) Components and their antioxidative activities of methanol extracts from sarcocarp and seed of Zizyphus jujuba var. Inermis rehder. Korean J Food Sci Technol, 38, 128-134

Choi SY, Lim SH, Kim JS, Ha TY, Kim SR, Kang KS, Hwang IK (2005) Evaluation of the estrogenic and antioxidant activity of some edible and medicinal plants. Korean J Food Sci Technol, 37, 549-556

Wang M, Li J, Rangarajan M, Shao Y, LaVoie EJ, Huang TC, Ho CT (1998) Antioxidative phenolic compounds from sage (Salvia officinalis). J Agr Food Chem, 46, 4869-4873 crossref(new window)

Kim JS, Lee YJ, Yang JF, Sa YJ, Kim MO, Park JH, Park DS, Yu CY, Kim MJ (2013) Biological activity of Sorghum bicolor M. cv. Bulgeunjangmoksusu extracts. Korean J Plant Res, 26, 111-118 crossref(new window)

Kwon HN, Park JR, Jeon JR (2008) Antioxidative and hepatoprotective effects of Acer tegmentosum M. extracts. J Korean Soc Food Sci Nutr, 37, 1389-1394 crossref(new window)

Kang YH, Park YK, Oh SR, Moon KD (1995) Studies on the physiological functionality of pine needle and mugwort extracts. Korean J Food Sci Technol, 27, 978-984

Labuza TP, Dugan Jr L (1971) Kinetics of lipid oxidation in foods. Crit Rev Food Sci, 2, 355-405

Pasko P, Barton H, Zagrodzki P, Gorinstein S, Folta M, Zachwieja Z (2009) Anthocyanins, total polyphenols and antioxidant activity in amaranth and quinoa seeds and sprouts during their growth. Food Chem, 115, 994-998 crossref(new window)

Dlamini NR, Taylor J, Rooney LW (2007) The effect of sorghum type and processing on the antioxidant properties of African sorghum-based foods. Food Chem, 105, 1412-1419 crossref(new window)

Choi HJ, Jeong YK, Kang DO, Joo WB (2008) Inhibitory effects of four solvent fractions of Alnus firma on ${\alpha}$-amylase and ${\alpha}$-glucosidase. J Life Sci, 18, 1005-1010 crossref(new window)

Jeong IK, Chung JH, Min YK, Lee MS, Lee MK, Kim KW, Chung YE, Park JY, Hong SK, Lee KU (2002) Comparative study about the effects of acarbose and voglibose in type 2 diabetic patients. J Korean Diabetes Assoc, 26, 134-145

Tsujimoto T, Shioyama E, Moriya K, Kawaratani H, Shirai Y, Toyohara M, Mitoro A, Yamao J, Fujii H, Fukui H (2008) Pneumatosis cystoides intestinalis following alpha-glucosidase inhibitor treatment: a case report and review of the literature. World J Gastroenterol, 14, 6087-6092 crossref(new window)

Jeong HJ, Lee SG, Lee EJ, Park WD, Kim JB, Kim HJ (2010) Antioxidant activity and anti-hyperglycemic activity of medicinal herbal extracts according to extraction methods. Korean J Food Sci Technol, 42, 571-577

Talesa VN (2001) Acetylcholinesterase in alzheimer's disease. Mech Ageing Dev, 122, 1961-1969 crossref(new window)

Houghton PJ, Ren Y, Howes MJ (2006) Acetylcholinesterase inhibitors from plants and fungi. Nat Prod Rep, 23, 181-199 crossref(new window)

Muir JL (1997) Acetylcholine, aging, and alzheimer's disease. Pharmacol Biochem Behav, 56, 687-696 crossref(new window)

Berkov S, Bastida J, Nikolova M, Viladomat F, Codina C (2008) Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. Phytochem Analysis, 19, 411-419 crossref(new window)

Mahinda S, Ahn CB, Je JY (2010) Enzymatic extracts from edible red algae, Porphyra tenera, and their antioxidant, anti-acetylcholinesterase, and anti-inflammatory activities. Food Sci Biotechnol, 19, 1551-1557 crossref(new window)

Jung MK, Park MS (2007) Acetylcholinesterase inhibition by flavonoids from Agrimonia pilosa. Molecules, 12, 2130-2139 crossref(new window)

Jeong HR, Jeong JH, Jo YN, Shin JH, Kang MJ, Sung NJ, Heo HJ (2011) Antioxidant and acetylcholinesterase inhibitory effect of aged raw garlic extracts. J Agr Life Sci, 45, 113-120