JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Concentration and Environmental Loading of Veterinary Antibiotics in Agricultural Irrigation Ditches
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Concentration and Environmental Loading of Veterinary Antibiotics in Agricultural Irrigation Ditches
Kim, Sung-Chul; Chung, Doug Young; Kim, Kye Hoon; Lee, Ja Hyun; Kim, Hyo Kyung; Yang, Jae E.; Ok, Yong Sik; Almarwei, Yaser A.O.;
  PDF(new window)
 Abstract
The concentration of veterinary antibiotics in aqueous and sediment matrices was measured in agricultural irrigation ditches bordering several animal-feeding operations (AFOs) and then compared to its concentration in the watershed. Analytical determination in aqueous samples was based on solid phase extraction (SPE) and appropriate buffer solutions were used to extract residuals in sediment samples. Separation and detection of extracted veterinary antibiotics were performed with high performance liquid chromatograph tandem mass spectrometry (HPLC/MS/MS). In general, higher concentrations of antibiotic were observed in the aqueous phase of irrigation ditches, with the highest concentration of erythromycin hydrochloride (ETM-) of , than in aqueous watershed samples. In contrast, higher concentrations were measured in river sediment than in irrigation ditch sediment with the highest concentration of oxytetracycline of . There was a high calculated correlation ( > 0.95) between precipitation and measured concentration in aqueous samples from the irrigation ditches for five of the ten targeted veterinary antibiotics, indicating that surface runoff could be an important transport mechanism of veterinary antibiotics from field to environment. Further, environmental loading calculation based on measured concentrations in aqueous samples and flow information clearly showed that irrigation ditches were 18 times greater than river. This result suggests the likelihood that veterinary antibiotics can be transported via irrigation ditches to the watershed. The transport via surface runoff and likely environmental loading via irrigation ditches examined in this study helps identify the pathway of veterinary antibiotics residuals in the environment.
 Keywords
Veterinary antibiotics;Irrigation ditch;Sediment;Transport;Environmental loading;
 Language
English
 Cited by
1.
Determining the distribution of pharmaceutically active compounds (PhACs) in soils and sediments by pressurized hot water extraction (PHWE), Chemosphere, 2017, 185, 1001  crossref(new windwow)
2.
Assessing antibiotic sorption in soil: a literature review and new case studies on sulfonamides and macrolides, Chemistry Central Journal, 2014, 8, 1, 5  crossref(new windwow)
 References
1.
Blackwell, P.A., H.H. Lutzhoft, H.P. Ma, B. Halling-Sorensen, A.B.A. Boxwell, and Kay, P. 2004. Ultrasonic extraction of veterinary antibiotics from soils and pig slurry with SPE clean-up and LC-UV and fluorescence detection. Talanta, 64:1058-1064. crossref(new window)

2.
Bruhn, S.T. 2003. Pharmaceutical antibiotic compounds in soils - a review. Journal of Plant Nutrition and Soil Science, 166:145 - 167. crossref(new window)

3.
Burkhardt, M., C. Stamm, C. Waul, H. Singer, and S. Muller. 2005. Surface runoff and transport of sulfonamide antibiotics and tracers on manured grassland. Journal of Environmental Quality, 34:1363-1371. crossref(new window)

4.
Campagnolo, E.R., K.R. Johnson, A. Karpati, C.S. Rubin, D.W. Kolpin, M.T. Meyer, and J.E. Esteban. 2002. Antimicrobial residuals in animal waste and water resources proximal to large-scale swine and poultry feeding operations. Science of the Total Environment, 299:89 - 95. crossref(new window)

5.
Castiglioni, S., R. Bagnati, R. Fanelli, F. Pomati, D. Calamari, and E. Zuccato. 2006. Removal of pharmaceuticals in sewage treatment plants in Italy. Environmental Science and Technology, 40:357-363. crossref(new window)

6.
Chee-Sanford, J.C., R.I. Aminov, I.J. Krapac, N. Garrigues-Jeanjean, and R.I. Mackie. 2001. Occurrence and diversity of tetracycline resistance genes in lagoons and groundwatr underlying two swine production facilities. Applied and Environmental Microbiology, 67:1494-1502. crossref(new window)

7.
Cromwell, G. 2002. Why and how antibiotics are used in swine production. Animal Biotechnology, 13:7. crossref(new window)

8.
Davis, J.G., C.C. Truman, S.C. Kim, J.C. Ascough, and K. Carlson. 2006. Antibiotic transport via runoff and soil loss. Journal of Environmental Quality, 35:2250-2260. crossref(new window)

9.
Diaz-Cruz, M.S., M.J.L. Alda, and D. Barcelo. 2003. Environmental behavior and analysis of veterinary and human drugs in soils, sediment and sludge. TRAC Trends in Analytical Chemistry, 22:340-351. crossref(new window)

10.
Gobel, A., C.S. McArdell, M.J.F. Suter, and W. Giger. 2004. Trace determination of macrolide and sulfonamide antimicrobials, a human sulfonamide metabolite, and trimethoprim in wastewater using liquid chromatography coupled to electrospray tandem mass spectrometry. Analytical Chemistry, 76:4756-4764. crossref(new window)

11.
Haller, M.Y., S.R. Muller, C.S. McArdell, A.C. Alder, and M.J.-F. Suter. 2002. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. Journal of Chromatography A, 952:111 - 120. crossref(new window)

12.
Hamscher, G., S. Sczesny, H. Hoper, and H. Nau. 2002. Determination of persistent tetracycline residues in soil fertilized with liquid manure by high performance liquid chromatography with electrospray ionization tandem mass spectrometry. Analytical Chemistry, 74:1509-1518. crossref(new window)

13.
Heberer, T. 2002. Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicology Letters, 131:5-17. crossref(new window)

14.
Hirsch, R., T. Ternes, K. Hanerer, and Kratz, K.L. 1999. Occurrence of antibiotics in the aquatic environment. Science of the Total Environment, 225:109-118. crossref(new window)

15.
Jacobsen, A.M., B. Halling-Sorensen, F. Ingerslev, and S.H. Gansen. 2004. Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1038:157-170. crossref(new window)

16.
Kay, P., P.A. Blackwell, and A.B.A. Boxall. 2004. Fate of veterinary antibiotics in a macroporous tile drained clay soils. Environmental Toxicology and Chemistry, 23:1136-1144. crossref(new window)

17.
Kay, P., P.A. Blackwell, and Boxall, A.B.A. 2005a. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. Environmental Pollution, 134:333-341. crossref(new window)

18.
Kay, P., P.A. Blackwell, and A.B.A. Boxall. 2005b. Transport of veterinary antibiotics in overland flow following the application of slurry to arable land. Chemosphere, 59:951-959. crossref(new window)

19.
Kim, S.C. and K. Carlson. 2007. Quantification of human and veterinary antibiotics in water and sediment using SPE/LC/MS/MS. Analytical and Bioanalytical Chemistry, 387:1301-1315. crossref(new window)

20.
Kim, S.C. and K.H. Carlson. 2006. Occurrence of ionophore antibiotics in water and sediments of a mixed-landscape watershed. Water Research, 40:2549-2560. crossref(new window)

21.
Kim, Y.H., T.M. Heinze, S.J. Kim, and C.E. Cerniglia. 2004. Adsorption and clay-catalyzed degradation of erythromycin A on homoionic clays. Journal of Environmental Quality, 33:257-264. crossref(new window)

22.
Kolpin, D.W., E.T. Furlong, M.T. Meyer, E.M. Thurman, S.D., Zaugg, L.B. Barber, and H.T. Buxton. 2002. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A National Reconnaissance. Environmental Science and Technology, 36:1202 - 1211. crossref(new window)

23.
Lidberg, R.H., K. Bjorklund, R. Rendahl, M.I. Johansson, M. Tysklind, and B.A.V. Andersson. 2007. Environmental risk assessment of antibiotics in the Swedish environment with emphasis on sewage treatment plants. Water Research, 41:613-619. crossref(new window)

24.
Liguoro, M.D., V. Cibin, F. Capolongo, B. Halling-sorensen, and C. Montesissa. 2003. Use of oxytetracycline and tylosin in intensive calf farming: evaluation of transfer to manure and soil. Chemosphere, 52:203-212. crossref(new window)

25.
Lindsey, M.E., M. Meyer, and E.M. Thurman. 2001. Analysis of trace levels of sulfonamides and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry. Analytical Chemistry, 73:4640-4646. crossref(new window)

26.
McArdell, C.S., E. Molnar, M.J.F. Suter, and W. Giger. 2003. Occurrence and fate of macrolide antibiotics in wastewater treatment plants and in the glatt valley watershed, Switzerland. Environmental Science and Technology, 37:5479-5486. crossref(new window)

27.
Mellon, M., C. Benbrook, and K.L. Benbrook. 2001. Hogging it: Estimation of antimicrobial abuse in livestock. Union of Concerned Scientists.

28.
Pedersen, J.A., M. Soliman, and I.H. Suffet. 2005. Human pharmaceuticals, hormons, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. Journal of Agricultural and Food Chemistry, 53:1625-1632. crossref(new window)

29.
Pei, R., S.C. Kim, K.H. Carlson, and A. Pruden. 2006. Effect of river landscape on the sediment concentration of antibiotics and corresponding antibiotic resistance genes (ARG). Water Research, 40:2427-2435. crossref(new window)

30.
Richardson, M.L. and J.M. Bowron. 1985. The fate of pharmaceutical chemicals in the aquatic environment. Journal of Pharmacy and Pharmacology, 37:1 - 12. crossref(new window)

31.
Rooklidge, S.J. 2004. Environmental antimicrobial contamination from terraccumulation and diffuse pollution pathways. Science of the Total Environment, 325:1-13. crossref(new window)

32.
Schlusener, M.P., K. Bester, and M. Spiteller. 2003. Determination of antibiotics such as macrolide, ionophores and tiamulin in liquid manure by HPLC-MS/MS. Analytical and Bioanalytical Chemistry, 375:942-947. crossref(new window)

33.
Sengelov, G., Y. Agerso, B. Halling-Sorensen, S.B. Baloda, J.S. Anderson, and L.B. Jensen. 2003. Bacterial antibiotic resistance levels in Danish farmland as a result of treatment with pig manure slurry. Environment International, 28:587-595. crossref(new window)

34.
Storteboom, H.N., S.-C. Kim, K.C. Doesken, K.H. Carlson, J.G. Davis, and A. Pruden. 2007. Response of antibiotics and resistance genes to high-intensity and low-intensity manure management. Journal of Environmental Quality, 36:1695-1703. crossref(new window)

35.
Thiele-Bruhn, S. 2003. Pharmaceutical antibiotic compounds in soil - a review. Journal of Plant Nutrition and Soil Science, 166:145-167. crossref(new window)

36.
Tolls, J. 2001. Sorption of veterinary pharmaceuticals in soils: A review. Environmental Science and Technology, 35:3397-3406. crossref(new window)

37.
USDA. 2003. Qualitative Identification of Tetracyclines in Tissues. United States Department of Agriculture Food Safety and Inspection Service.

38.
Zhu, J., D.D. Snow, D.A. Cassada, S.J. Monson, and Spalding, R.F. 2001. Analysis of oxytetracycline, tetracycline, and chlorotetracycline in water using solid-phase extraction and liquid chromatography tandem mass spectrometry. Journal of Chromatography A, 928:177 - 186. crossref(new window)