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A comparison of the effects of dexamethasone-pharmacopuncture and dexamethasone-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice
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  • Journal title : TANG [HUMANITAS MEDICINE]
  • Volume 3, Issue 3,  2013, pp.24.1-24.5
  • Publisher : Association of Humanitas Medicine
  • DOI : 10.5667/tang.2013.0017
 Title & Authors
A comparison of the effects of dexamethasone-pharmacopuncture and dexamethasone-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice
Kim, Jaehak; Kang, Doyoung; Kang, Minsu; Kang, Bora; Kang, Eun Byeol; Kang, Jinseok; Go, YaeJin; Ko, Wheehyoung; Kwak, JaeYoung; Ku, Hyunjung; Gwon, Seo Yeon; Gi, Yumi; Kim, Gayeon; Kim, GyeongMuk; Kim, Kyunghoon; Kim, Kyuri; Kim, Dong Hyun; Kim, MinWoo; Kim, Min Chae; Kim, Seongho; Kim, Seyoon; Kim, Shilla; Kim, ShinHyung; Kim, Young-Jun; Kim, JongHyeon;
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Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between dexamethasone-pharmacopuncture (DP) and dexamethasone-oral administration (DO), the effect of DP was investigated in murine models. Anti-anaphylactic effects of dexamethasone treatments were investigated in compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and passive cutaneous anaphylaxis (PCA). DP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and PCA. The effects between DP and DO were on a similar level. These results indicate that DP can be used as an alternative method for DO in case of emergency.
dexamethasone-pharmacopuncture;systemic anaphylactic reaction;ear swelling response;passive cutaneous anaphylaxis;
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