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Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea
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 Title & Authors
Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea
Kim, Kiju; Park, Yookyung; Park, Bokyung; Truong, Quang Lam; Park, Soyeon; Kim, Jaehun; Hahn, Tae-Wook;
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Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in Korea, and these outbreaks have since continuously occurred. In the present study, we determined the full-length nucleocapsid (N) gene sequences of three Korean PEDV field isolates collected in 2014-2015. Sequence and phylogenetic analysis of N genes revealed that recent prevalent Korean PEDV isolates were very closely related to the US PEDV isolates in 2013. Interestingly, the phylogenetic tree based on the nucleotide sequencing of the PEDV N gene was similar to the tree topology of the PEDV complete genomes. Therefore, our data provide a better understanding of the genetic diversity and contribute to the accurate diagnosis and development of vaccines against PEDV.
Korean isolates;N gene;nucleocapsid;porcine epidemic diarrhea virus;phylogenetic analysis;
 Cited by
충남지역 돼지유행성설사 바이러스 Spike 유전자 염기서열 및 계통분석,박효선;육심용;전동민;이진주;신창호;

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