Analysis of chemical mediators and cytokines in allergic inflammation models in rats and their advantages for the screening of anti-allergic inflammatory drugs
- Ohuchi, Kazuo (Department of Pathophysiological Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku University)
- Published : 1996.04.01
We have established an air pouch-type allergic inflammation model in rats [1,2] and a peritoneal eosinophilia model in rats . Employing the two models, chemical mediators and cytokines responsible for the development of inflammation induced by at allergic mechanisms are investigated to clarify the usefulness of the two models for the screening of anti-allergic inflammatory drugs.