The potential pollution problems resulting from tanker collision necessitate the requirement for an effective structural design and the development of relevant safety regulation. During a few decades, the great effort has been made by International Maritime Organization and the Administration, etc, to reduce oil spillage from collision accidents. However there is still a need for investigation in the light of structural evaluation method for the experiments and rational analysis, and design development for an operational purpose of ships. This study is aimed at investigating a complicated structural response of bow structures of oil carriers for assessing the energy dissipation and crushing mechanics of striking vessel through a methodology of the numerical analysts for the various models and its design changes. Through this study an optimal bow construction absorbing great portion of kinetic energy in the least penetration depth prior to reach to the cargo area and an effective location of collision bulkhead are investigated. In order to obtain a rational results in this study, three stages of response analysis procedures are performed as follows; 1). 16 simplified ship models are used to investigate the structural response against bow collision with variation of primary and secondary members. Mass and speed are also varied in two conditions. 2). 21 models conisted of 5 size of full scaled oil carriers are used to perform the collision simulation with the various sizes and deadweight delivered in a recent which are complied with SOLAS and MARPOL. 3). 36 models of 100k oil carrier are used to investigate the structural response and its influence to the collision bulkhead against bow collision in variation with location of collision bulkhead, primary mombers, framing system and colliding conditions, etc.