Recently continuous welded rail is generally used to ensure running performances and to overcome the problems such as structural vulnerability and fastener damage at the rail expansion joint. Though the use of continuous welded rail on bridge has the advantage of decreasing the vibration and damage of rail, it still the risk of buckling and breaking of rail due to change of temperature, starting and/or breaking force, axial stress concentration and so on. So, VIC code and many methods has been developed by researchers considering rail-bridge interaction. Although there are many research concerning stability of continuous welded rail about temperature change on bridge and starting and/or breaking force, the study of continuous welded mil for earthquake load is still unsufficient. In this study, the nonlinear seismic response analysis of continuous welded rail on bridge considering soil-structure interaction, geotechnical characteristic of foundation and earthquake isolation equipment has been performed to examine the stability of continuous welded rail.