Syntheses of Substituted tert.-Butyl(o-tolyl)-perpropionates

tert.-Butyl ${\beta}$-(o-tolyl)-perpropionate 치환체들의 합성

  • Hahn, Chi-Sun (Department of Chemistry, Yonsei University) ;
  • Martin, Michael M. (The University of Michigan)
  • Published : 19641200


The syntheses of substituted tert.-butyl ${\beta}$-(o-tolyl)- perpropionates via intermediates obtained by chloromethylation, malonic syntheses and decarboxylation is described. The intermediates substituted with a group possessing moderate substituent effect such as bromo, chloro, and methyl group were obtained in good yields. The nitro-substituted intermediat was obtained in poor yield. The chloromethylation of toluenes containing electron donating groups resulted in polymerization.



  1. Free Radicals in Solution C. Walling
  2. J. Am. Chem. Soc. v.72 S. G. Cohen;D. B. Sparrow
  3. J. Am. Chem. Soc. v.72 F. Strain(et al.)
  4. J. Am. Chem. Soc. v.73 A. T. Blomquist;A. F. Ferris
  5. J. Org. Chem. v.19 H. C. McBay;O. Tucker
  6. J. Chem. Soc. W. Cooper
  7. J. Chem. Soc. A. G. Davies;K. J. Hunter
  8. Ber. v.17 J. V. Brown;J. Nelles
  9. Org. Reac. v.I R. C. Fuson;C.H. McKeever
  10. J. Chem. Soc. G. R. Clemo;G. A. Swan
  11. J. Chem. Soc. W. Cooper
  12. J. Am. Chem. Soc. v.73 A. T. Blomquist;J. A. Bernstein