Study of 8-Hydroxyquinoline Derivatives. The Acid Dissociation Constants of 5-Acetyl-8-Hydroxyquinoline

8-Hydroxyquinoline 誘導體에 關한 硏究 5-Acetyl-8-Hydroxyquinoline의 酸解離定數

  • Lee, Dong-Hyung (Department of Chemistry, College of Liberal Arts and Sciences, Chonnam National University)
  • 이동형 (全南大學校 文理科大學 化學科)
  • Published : 19650300

Abstract

Acid dissociation constants of 5-acetyl-8-hydroxyquinoline have been determined by spectrophotometric and potentiometric methods at $25^{\circ}C$. $pK_1$, $pK_2$ values obtained by potentiometric method were 4.56, 8.20 respectively and $pK_1$ obtained by spectrophotometric method was 4.21. pK values were lower than those of 8-hydroxyquinoline. The lower basicity of 5-acetyl-8-hydroxyquinoline compared with 8-hydroxyquinoline was considered as the result of the electronic attraction of the acetyl group with aromatic ring.

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References

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