- Volume 11 Issue 1
The effects of n-hexane and tetrachlorodiphenyl on the growth rate, the blood picture and histopathological change induced were observed in chicken. A total of 350 chicken were fed various daily dosages of n-hexane and tetrachlorodiphenyl for the experimental period of 60 days. The results obtained were as follows. 1. The growth rate of chicken in the group fed 100 ppm of tetrachlorodiphenyl was reduced (p<0.05). However no significant results were observed in the other dosage groups. 2. The reduction of the growth rate was found only in the liver and the kidney but not found in the other orgns. 3. No significant results were found in the number of erythrocytes and hematocrit value. However, the number of leukcocytes of chicken in the group fed 100 ppm of tetrachlorodiphenyl was significantly low. 4. In both n-hexane and tetrachlorodiphenyl groups, the number of lymphocytes was found to decrease but the number of basophiles and eosinophiles were found to increase (p<0.05). 5. All the chicken fed 300 ppm of tetrachlorodiphenyl died between 7th and 9th days. 6. Fatty change of hepatic cells and cloudy swelling of epithelia of renal tubules were found in the group fed 0.5 ml of n-hexane. However, in the group fed more the 100 ppm, fatty change of hepatic cells was followed by necrosis and comparatively severe cloudy swelling was found in epithelia of renal tubules.