Studies on the Synthesis of Cyclitol derivatives -Part 6. Synthesis of O-(5-nitro-2-furoyl)-inositols and their test for food industry-

Cyclitol 유도체(誘導體) 합성(合成)에 관(關)한 연구(硏究) -제(第)6보(報) O-(5-nitro-2-furoyl)-inositol류(類)의 합성(合成)과 식품공업상(食品工業上) 응용(應用)을 위한 시험(試驗)-

  • 손주환 (인하대학교 공과대학 화학공학과) ;
  • 김용인 (홍익대학교 이공대학 화학공학과) ;
  • 박영랑 (인하대학교 공과대학 화학공학과)
  • Published : 1973.12.28


In the previous work, as we have reported on the reduction of penta-O-acetyl-myo-inosose-2 and penta-O-acetyl-DL-epi-inosose-2, axial and equatorial alcohol have been produced. The synthesis of various inositol 5-nitro-2-furoate are described. The esters have been obtained by reaction of 5-nitro-2-furoylchloride with inositol stereomers in chloroform at low temperature. The ester have been characterized by paper chromatography and other determination. For the applicable purpose of food industry, their antimicrobial activities on microbes were tested, and it was found that the antimicrobial activity of muco-inositol ester was superior to the others, and considered that result would be related to the stereochemical structure.