Sweet Taste Mechanism of 1-Alkoxy-4-nitroaniline

1-알콕시-4-니트로아닐린들의 糖度에 關한 硏究

  • U. R. Kim (Catholic Medical College) ;
  • M. S. Jhon (The Korea Advanced Institute of Science) ;
  • Y. B. Chae (Korea Institute of Science & Technology)
  • Published : 1973.12.30

Abstract

A semiempirical molecular orbital theory which is known as extended H ckel theory is applied to explain the sweet taste mechanism of nitroaniline, 1-methoxy-4-nitroaniline, and 1-ethoxy-4-nitroaniline which has different sweetness respectively. In this paper, the assumption is made that the nitroaniline is coplanar. The relationship between charge density and sweetness has been calculated according to the geometrical rotation of the orthosubstitute of nitroanilines. It has been shown that the calculated results are consistent with the experimental order of the relative sweetness.

Keywords

References

  1. Rec. Trav. Chim. v.59 J.J. Blanksma;P.W.M. van der Weyden
  2. Rec. Trav. Chim. v.65 J.J. Blanksma;P.W.M. van der Weyden
  3. Rec. Trav. Chim. v.68 P.E. Verkade(et al.)
  4. J.Chem. Phys. v.39 R.J.Hoffman
  5. Valence C.A.Coulson
  6. J.Chem. Phys. v.20 M. Wolfsberg;L.Hermholtz
  7. Trans. Faraday Soc. v.49 H.A.Skinner;H.O.Pritchard
  8. Chem. Rev. v.55 H.O. Pritchard;H.A. Skinner
  9. Rec.Trav. Chim. v.85 B.P.Van. Eijck
  10. J. Chem. Soc., (A) G. Govil
  11. Bull.Chem. Soc. Japan v.42 K. Fukui(et al.)
  12. Fette-Seifen-Anstrichimittel v.57 H.P. Kaufmann;D. Schweizer
  13. J.Chem.Ed. v.35 L.N. Ferguson;A.R. Lawthnence
  14. Nature v.186 E.J. Barnes;L.N. Ferguson
  15. J.Org.Chem. v.25 L.N. Ferguson;L.G. Childers
  16. Chemistry in Can. 2 no.6 H.R. Frisch
  17. J.Org.Chem. v.25 A.R. Lawrence;L.N.Ferguson
  18. Nature v.183 A.R. Lawrence;L.N. Ferguson