Effect of Aflatoxin on the Growth of Bacillus megaterium

Aflatoxin이 Bacillus megaterium의 생육(生育)에 미치는 영향

  • Choi, Eon-Ho (Agricultural Biochemistry Laboratory, Korea Atomic Energy Research Institute) ;
  • Lee, Kwan-Young (Agricultural Biochemistry Laboratory, Korea Atomic Energy Research Institute) ;
  • Lee, Su-Rae (Agricultural Biochemistry Laboratory, Korea Atomic Energy Research Institute)
  • 최언호 (한국원자력연구소 농업생화학연구실) ;
  • 이관영 (한국원자력연구소 농업생화학연구실) ;
  • 이서래 (한국원자력연구소 농업생화학연구실)
  • Published : 1976.03.28

Abstract

Growth inhibition and morphological alteration of Bacillus megaterium NRRL B-1368 in aflatoxin-containing TGY liquid media and its growth restoration in normal media were investigated. Crude aflatoxins $(B_1\;22.7%,\;B_2\;1.6%,\;G_1\;3.6\;%\;and\;G_2\;0.2%)$ at concentrations of more than $20{\mu}g/ml$ inhibited the growth of the microorganism and prevented the formation of septum, resulting in abnormal elongation and disturbance of cell division. The aberrant cells, however, grew normally by septum formation and cell division upon returning to aflatoxin-free culture media. It was, therefore, assumed that aflatoxin affects the function of mesosome related to septum formation in bacteria.

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