Studies on Enteric Colibacillosis in Piglets 3. A Field Trial of Polyvalent Live Escherichia coli Oral Vaccine

자돈(仔豚)의 병원성(病源性) 대장균증(大腸菌症)에 관한 연구(硏究) 3. 임신모돈(姙娠母豚)에 대한 대장균생균(大腸菌生菌)백신의 경구투여(經口投與)가 자돈(仔豚)의 대장균(大腸菌)설사병 예방(豫防)에 미치는 영향(影響)

  • Kim, Bong-Hwan (Department of Veterinary Medicine, College of Agriculture, Gyeongsang National University)
  • Published : 1982.10.09


A polyvalent live Escherochia coli oral vaccine were prepared by the use of 5 field isolates of enteropathogenic E. coli, serotypes 08 : K87, K88a, b ; 0138 : K81, K88a, c ; 0141 : K85a, b, K88a, b ; 0149 : K91, K88a, c and 0157 : K'V17', K88a, c. Some field experiments were conducted to investigate the effectiveness of the polyvalent live E. coli oral vaccine in the prevention of neonatal colibacillosis in piglets suckling orally vaccinated sows. Seventy-nine pregnant sows in an intensive pig farm were vaccinated with oral vaccine 4 weeks prior to farrowing and 19 sows were chosen for control. The piglets suckling vaccinated sows showed a significant protection against neonatal enteric colibacillosis during the 2 weeks observation period from the farrowing but no significant differences in protection between vaccinated and control group were observed with piglets older than 15 days.