Automation of Glutamic Acid Fermentation

글루탐산 발효공정의 자동화

  • Park, S.H. (Foods R&D Center, Cheil Sugar Co., Ltd.) ;
  • Hong, K.T. (Foods R&D Center, Cheil Sugar Co., Ltd.) ;
  • You, S.J. (Foods R&D Center, Cheil Sugar Co., Ltd.) ;
  • Lee, J.H. (Foods R&D Center, Cheil Sugar Co., Ltd.) ;
  • Bae, J.C. (Foods R&D Center, Cheil Sugar Co., Ltd.)
  • Published : 1983.01.01

Abstract

A strategy for the automation of glutamic acid fermentation has been developed by the use of $CO_2$ analyzer together with a controller. It was found that a linear relationship existed between growth and $CO_2$ level in the exit gas. Therefore penicillin addition at an appropriate biomass concentration to excrete glutamate could be achieved automatically. In addition, an automatic batch feeding method (fed-batch culture) provided a means of overcoming substrate inhibition effects on growth and glutamic acid production in batch culture, thereby increasing productivity and product yield.

Keywords