The Antibacterial Activities of Lysozyme Isolated from the Egg White of Ogol Fowl

오골계 난백에서 분리한 Lysozyme의 항균작용

  • Oh, Hong-Rock (Dept. of Animal Sci., Chungnam National University) ;
  • Bae, Ki-Hwan (Dept. of Pharmacy, Chungnam National University)
  • 오홍록 (충남대학교 농과대학 축산학과) ;
  • 배기환 (충남대학교 약학대학 약학과)
  • Published : 1987.11.30


A lysozyme is isolated and purified partially form the egg white of Korean native Ogol fowl(Natural monument No. 265) by the method of direct crystallization. The bacteriolytic activities of 1% lysozyme against Staphylococus aureus 57, Bacillus subtilis ATCC 6633, and Escherichia coli NIHJ-JC2 was investigated with or without some other antibacterial materials in the nutrient broth culture. According to the results, 1% lysozyme showed the appreciable bacterolytic activities of about 12-16% to the almost of bacteria cultured. The synergistic effect with the lysozyme and some antibacterial materials on the growth inhibition of the bacteria cultured exhibited higher in order of the 0.001% magnolol -22%, the 0.001% honokiol -14% against S. aureus and of the 0.0005% erythromcin -29%, the honokiol -22%, the magnolol -l7%, the 0.005% phospholipase -6% against E. coli. And that synergistic effect against B. subtilis showed a fairly high level of about 52% with the erythromycin but not any effect with others.