- Volume 28 Issue 1
Electron Microscopic Observations of the Vascular Endothelial Cells in the Central Nervous System of Piglets Infected with Porcine Enterovirus Serotype 3
Porcine Enterovirus 감염자돈(感染仔豚)의 중추신경계(中樞神經系) 혈관내피세포(血管內皮細胞)의 전자현미경적(電子顯微鏡的) 관찰(觀察)
- Shin, Tae-kyun (Department of Anatomy, College of Medicine, Chungnam National University) ;
- Lee, Cha-soo (College of Veterinary Medicine, Kyungpook National University)
- Received : 1988.01.14
- Published : 1988.04.30
In the course of studying porcine enterovirus infection in piglets, the vascular endothelial cells in the CNS of colostrum-deprived piglets with polioence-phalomyelitis were investigated by electron microscope. The experimental piglets were orally infected with the porcine enterovirus serogroup 3 isolated in Korea and necropsied at 7 days postinoculation. Crystalline arrays of viral particles were found in the vascular endothelial cells of the spinal cord and cerebellum. Aggregates of immature viral particles were occasionally observed in the vascular endothelial cells in the meninges. The rough ER was deprived of ribosomes, irregularly dilated and associated with viral crystals, There were abundant cytoplasmic filaments, dilatation of perivascular space, perivascular cuffing, and the partial distruptions of endothelial cell membrane and basal lamina.