Production of ${\gamma}$-Linolenic Acid by Mortierella isabellina IFO 8183

Mortierella isabellina IFO 8183에 의한 ${\gamma}$-Linolenic Acid 생산

  • Yang, Dong-Hyun (Research and Development Center, Nong Shim Co., Ltd.) ;
  • Nam, Hee-Sop (Research and Development Center, Nong Shim Co., Ltd.) ;
  • Lee, Sang-Hyub (Department of Agricultural Chemistry, Korea University) ;
  • Bang, Won-Gi (Department of Agricultural Chemistry, Korea University)
  • 양동현 ((주) 농심 기술개발연구소) ;
  • 남희섭 ((주) 농심 기술개발연구소) ;
  • 이상협 (고려대학교 농과대학 농화학과) ;
  • 방원기 (고려대학교 농과대학 농화학과)
  • Published : 1989.12.01


To produce ${\gamma}-linolenic$ acid by a mold, cultural conditions of Mortierella isabellina IFO 8183 were investigated. It was found that the increase of initial pH resulted in the decrease of the ${\gamma}-Linolenic$ acid content and the increase of the C/N ratio of medium resulted in the increase of the lipid content. Addition of sodium acetate into the medium resulted in the increased of cell yield, lipid yield, ${\gamma}-Linolenic$ acid content and ${\gamma}-Linolenic$ acid productivity. Under the optimum coditions(glucose, $NH_4NO_3$, C/N ratio of 40, pH 6.0, $30^{\circ}C$ and 0.5% of sodium acetate), the following results were obtained: cell yield, 0.347(g dry biomass/g glucose; lipid yield, 0.18(g lipid/g glucose); lipid content, 0.52(g lipid/g dry biomass); ${\gamma}-linolenic$ acid content, 60(mg ${\gamma}-linolenic$ acid/g lipid); maximum ${\gamma}-linolenic$ acid concentration, 347mg/l after incubation of 8 days.


${\gamma}$-linolenic acid;fungal oil;mortierella isabellina