The Facile Synthesis of Pyrrolidinobenzenes from Succinaldehyde and Phenylenediamines using HFe(CO)$_4^-$

사카르보닐 철산염, HFe(CO)$_4^-$을 이용한 숙신알데히드와 페닐렌디아민으로부터 피로리디노벤젠의 편리한 합성

  • Published : 19901100

Abstract

Ethanolic tetracarbonylhydridoferrate, HFe(CO)$_4^-$, combined with aqueous succinaldehyde is very efficient for the selective transformation of an amino group into a pyrrolidine ring. Phenylendiamines react with aqueous succinaldehyde in the presence of HFe(CO)$_4^-$, at room temperature under atmospheric pressure of carbon monoxide to give the corresponding pyrrolidines in moderate yields. In these reactions, the molar ratio of 1.0:1.0:1.0 of the ferrate-succinaldehydephenylenediamine system gave one pyrrolidine ring, and the case of 1.0:2.0:1.0 gave two pyrrolidine rings, selectively.

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References

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