Hematological and blood chemical changes of rabbits infected with viral hemorrhagic disease virus

토끼 출혈성 바이러스에 감염된 토끼의 혈액상과 혈액화학치의 변화

  • Yoon, In-joong (College of Veterinary Medicine, Seoul National University) ;
  • Jeon, Yun-seong (College of Veterinary Medicine, Seoul National University)
  • 윤인중 (서울대학교 수의과대학) ;
  • 전윤성 (서울대학교 수의과대학)
  • Received : 1989.12.30
  • Published : 1990.01.31

Abstract

Hematological and blood chemical changes of rabbits infected with rabbit hemorrhagic disease virus were studied and the results were summarized as follows: 1. Total leukocyte count ($2,410{\pm}1,076/{\mu}l$), lymphocyte count ($1,582{\pm}632.5{\mu}l$) and heterophil count ($705{\pm}411.1{\mu}l$) were significantly decreased after 24 hours of the infection (p<0.01). However, no significant changes were observed in monocyte, eosinophil and basophil numbers. 2. A significant increase of aspartate aminotransferase (96IU/L), alanine aminotransferase (96IU/L) and alkaline phosphatase ($401.1{\pm}131.8IU/L$) was observed (p<0.01). 3. A moderate increase of BUN ($26.9{\pm}3.6mg/100ml$) and creatinine ($3.2{\pm}1.9mg/100ml$) was observed (p<0.05). 4. No significant changes of r-GTP, thymol turbidity, glucose, cholesterol, albumin, total serum protein, fibrinogen were observed.