Virological studies on the puppies experimentally infected with canine parvovirus isolated in Korea

환견으로 부터 분리한 canine parvovirus의 실험적 감염 자견에 대한 바이러스학적 연구

  • Choi, Hae-yeon (Northern Branch of Chungbuk Animal Health Laboratory) ;
  • Jun, Moo-hyung (College of Veterinary Medicine, Chungnam National University) ;
  • Park, Seong-kuk (College of Veterinary Medicine, Chungnam National University)
  • 최해연 (충북가축위생시험소 북부지소) ;
  • 전무형 (충남대학교 수의과대학) ;
  • 박성국 (충남대학교 수의과대학)
  • Received : 1991.03.10
  • Published : 1991.07.31


To investigate the pathogenicity and virological properties of TJ-89-2 strain of canine parvovirus(CPV -2) that was isolated from the diseased puppies in Korea, seven puppies-were inoculated intraorally with the isolate at the HA titer of 8,192. All of the puppies showed the signs of anorexia, vomiting, diarrhea and died at the 5th to 10th days post inoculation (pi). All of the fecal samples from the puppies revealed significantly high HA titers afterward the 5th days pi. Body temperature and the number of total leucocytes were slightly increased at the early stage of infection, but extremly decreased at the stage of collapse. HI titers of the sera began to increase at the 3rd to 4th days pi, reaching 512 to 1,024 at the 4th to 5th days pi.