Studies on Antimicrobial Substances of Canoderma lucidum

영지의 항균성 물질에 관한 연구

  • Chung, Dong-Ok (Il Yang Pharmaceutical Company Research Institute) ;
  • Jung, Ji-Heun (Department of Food Science and Technology, Chonnam National University)
  • Published : 1992.12.01


To study antibacterial activities of Ganoderma lucidum, its extract was fractionated by various organic solvents with different polarities and the fractions were purified by thin layer chromatography and silica gel column chromatography. The results of antibacterial test of the extracts showed that antimicrobial activities were detected in fractions B and E of the ethylacetate extract. The minimum inhibitory concentration (MIC) of fraction B to Staphylococcus aureus and to Salmonella typtimurium were 0.8% (8,000 ppm). MIC of fraction E to Staphylococcus aureus was 0.185% (1,875 ppm).