Ultrastructure of virus particles in the liver of piglets infected with porcine enterovirus serotype 3

Enterovirus 감염 돼지의 간에서 virus의 형태학적 관찰

  • Shin, Tae-kyun (Department of Veterinary Medicine, Cheju National University) ;
  • Lee, Cha-soo (College of Veterinary Medicine, Kyungpook National University) ;
  • Huh, Min-do (Department of Fish Pathology, National Fisheries University of Pusun)
  • 신태균 (제주대학교 수의학과) ;
  • 이차수 (경북대학교 수의과대학) ;
  • 허민도 (부산수산대학교 어병학과)
  • Received : 1991.10.16
  • Published : 1992.04.30


Oral infection of colostrum-deprived, neonatal piglets with porcine enterovirus serotype 3 can result in hepatic lesions with a short incubation period. In the thin section of the affected liver, crystalline arrays of virus particles characteristic of picornavirus were identified in the sinusoid endothelial cells and Kupffer cells. There were also cytoplasmic aggregates of electron- dense, virus-like particles in the hepatocytes. These findings suggest that porcine enterovirus serotype 3 has hepatotropism as well as neurotropism.