Effects of the Feeding Platycodon grandiflorum and Codonopsis Ianceolata on the Fatty Acid Composition of Serum and Liver in Rats

도라지 및 더덕 첨가식이가 흰쥐의 혈청 및 간장의 지방산 조성에 미치는 영향

  • 김소영 (경상대학교 식품영양학과) ;
  • 김한수 (경상대학교 식품영양학과) ;
  • 김성희 (경상대학교 식품영양학과) ;
  • 김희숙 (진주전문대학 식품영양과) ;
  • 서인숙 (경상대학교 식품영양학과) ;
  • 정승용 (경상대학교 식품영양학과)
  • Published : 1993.10.01

Abstract

This study was designed to observe the effects of the feeding Platycodon grandiflorum, Codonopsis Ianceolata, perilla oil and safflower oil on the fatty acid composition in serum and liver of dietary hypercholesterolemic rats. Experimental groups mixed with 5% cellulose +10% lard (group 1, control group), 2% cholestyraemine +10% lard (group 2), 5% C. ianceolata+ 10% perilla oil (group 3), 5% P. grandiflorum+10% perilla oil (group 4), 5% C. ianceolata+10% safflower oil (group 5) and 5% P. grandiflorum+10% safflower oil (group 6) were administered to the male rats of the Sprague Dawley for 3 weeks. In the fatty arid compositions of serum total fatty arid, phospholipid, triglyceride and cholesteryl ester, the linoleic acid content was most in the PUFA and it was major fatty acid. Particularly, the other components except the phospholipid fraction in serum lipids were influenced by the fatty acid composition of the test lipids from the fact that linoleic acid content was remarkably more in the groups 5 and 6. In the fatty arid compositions of liver total fatty acid, phospholipid, triglyceride and cholesteryl ester, the linoleic acid content was more in the PUFA and so it was major fatty acid. Particularly, the arachidonic and eicosapentaenoic acid contents of phospholipid fraction in liver lipids were rather more. from the above research, fatty arid composition of serum and liver lipid components were influenced by the fatty acid composition of the test lipids from the fact that linoleic acid takes up the highest percentage.