Iterative Regression Optimization of Two-Parameters in Micellar Liquid Chromatography

미셀 액체 크로마토그래피에서 두 가지 파라미터의 반복 회귀 최적화

  • Kim, In-Whan (Department of Chemistry Education, Taegu University) ;
  • Kim, Sang-Tae (Department of Chemistry, The Third Military Academy)
  • 김인환 (대구대학교 사범대학 화학교육과) ;
  • 김상태 (육군 제3사관학교 대학부 화학과)
  • Received : 1993.04.10
  • Published : 1993.08.25


The iterative regression optimization strategy using two parameters is described and applied to the separation of amino acids and peptides by means of micellar liquid chromatography. The parameters examined are concentration of surfactant and 2-propanol. This approach results in a efficient optimization using a small number of initial experiments.


Micellar Liquid Chromatography;Optimization Separation of Amino acids and Peptides