There have been traditional approaches to model radio propagation path loss mechanism both theoretically ad empirically. Theoretical approach is simple to explain and effective in certain cases. Empirical approach accommodates the terrain configuration and distance between base station and mobile unit along the propagation path only. In other words, it does not accommodate natural terrain configuration over a specific area. In this paper, we propose a spatial prediction technique for the mobile radio propagation path loss accommodating complete natural terrain configuration over a specific area. Statistical uncertainty analysis is also considered.