Effects of Krill and Cadmium on Lipid Composition of Plasma in Cholesterol-Fed Rats

크릴과 카드뮴이 콜레스텔롤 식이 흰쥐의 혈장지질에 미치는 영향

  • 손미예 (서울대학교 보건대학원) ;
  • 정문호 (서울대학교 보건대학원) ;
  • 박석규 (순천대학교 식품영양학과) ;
  • 조영숙 (순천대학교 식품영양학과)
  • Published : 1994.02.01

Abstract

To investigate the effects of krill and cadmium on lipid composition of plasma in cholesterol-fed rats, male Sprague-Dawley rats were raised for 4 weeks with 8 experimental diets. The cholesterol, ${\beta}-lipoprotein$, phospholipid and triglyceride concentration of plasma in rats fed krill diets containing below 5%9w/w) krill were not significant differences in comparison with those of control diet. The ingestion of cadmium caused a significant increase in free cholesterol 91.6-fold), triglyceride 91.6-fold), ${\beta}-lipoprotein$(1.4-fold) and total cholesterol (1.3-fold) level, and then HDL-cholesterol concentration of cadmium diet was 1.6-fold lower than that of control diet. The krill supplement of cadmium diet rather resulted in a increase in total cholesterol, free cholesterol, ${\beta}-lipoprotein$ and triglyceride concentration of plasma.

References

  1. 대한의학협회지 v.28 심맥질환의 임상병리검사 김상인;김진규
  2. Annu. Rev. Biochem. v.46 The low-density lipoprotein pathway and its ralation to atherosclerosis Goldstein,J.L.;Brown,M.S.
  3. J. Nutr. Sci. Vitaminol. v.30 Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet Kobatake,Y.;Kuroda,K.;Jinnouchi,H.
  4. 한국영양식량학회지 v.15 미역첨가급식이 흰쥐의 간 및 혈청의 지질농도에 미치는 영향 한재금;고진복
  5. 한국영양학회지 v.21 율무쌀이 쥐의 혈장콜레스테롤 및 지질대사에 미치는 영향 박양자;이영선;영목평광
  6. 한국영양식량학회지 v.13 토룡분 첨가급식이 흰쥐의 성장 및 혈액 성분에 미치는 영향 백정희;고진복
  7. 한국영양식량학회지 v.13 홍삼 및 도라지 분말이 흰쥐의 혈장 및 간 지질에 미치는 영향 노경희;김을상
  8. Arch. Environ. Health v.24 Cadmium and zinc binding in mammalian liver and kidneys Shaikh,Z.A.;Lucis,O.J.
  9. Japan. J. Pharmacol. v.35 Defense mechanisms against cadmium toxicity. I. A biochemical and histological study of the effects of pretreatment with cadmium on the acute oral toxicity of cadmium in mice Morita,S.
  10. J. Appl. Toxicol. v.5 Cd-metallothionein induced nephropathy : a morphological and autoradiographical study of Cd distribution, the development of tubular demage and subsequent cell regeneration Murakami,M.;Cain,K.;Webb,M.
  11. Toxicology v.34 Effects of three proteins on absorption of Cd in rats Kojima,S.
  12. Environ. Health Prespect v.54 Dietary protein effects on Cd and metallothionein accumulation in the liver and kidney of rats Revis,N.M.;Osborne,T.R.
  13. Official methods of analysis(15th ed.) A.O.A.C.
  14. 생물농업실험실통계학 조재성;이광전
  15. 食の枓學 v.139 ナンキョクオキアミの生態 遠藤 宜成
  16. 한국수산학회지 v.12 남대양산 크릴의 이용에 관한 연구, 1. 크릴의 식품영양학적인 성상 박영호;이응호;이강호;변재형;류홍수;최수안;김선봉
  17. 한국수산학회지 v.18 크릴을 원료로 한 식품가공용 중간소재 (크릴페이스트)가공에 관한 연구 이응호;차용준;오광수;구재근
  18. J. Lipid Res. v.21 Effects of dietary protein on turnover, oxidation and absorption of cholesterol and on steroid excretion in rabbits Huff,M.W.;Carroll,K.K.
  19. Eur. J. Clin. Invest. v.1 Plasma lecithin cholesterol acyltransferase activity in liver disease Calandra,S.;Martin,M.J.;Mcintyre,N.
  20. J. Nutr. v.112 Effect of on oral dose of vitamin E on the cholesterol content of tissues of the vitamin E-deficient rat Kaseki,H.;Kim,E.Y.
  21. 한국영양식량학회지 v.19 카드뮴 투여 흰쥐의 혈청 및 간장성분에 미치는 식이성 비타민 E와 단백질의 영향 김혜진;조수열;박종민
  22. 한국영양식량학회지 v.21 고콜레스테롤증 유발 흰쥐에 있어서 버섯류가 지질성분에 미치는 영향 김군자;김한수;정승용
  23. The transport and turnover of the plasma cholesterol in plasma lipoprotein Myaant,N.B.;Smellie,R.M.S.(ed.)
  24. Pro. Nat. Acad. Sci. v.78 Regulatory role for hepatic low density lipoprotein receptors in vivo in the dogs Kovanen,P.T.;Bilheimer,D.W.;Goldstein,J.L.;Jaramillo,J.J.;Brown,M.S.
  25. Biochim. Biophys. Acta v.218 Human lipoprotein lipase inhibition of activity by cholesterol Fielding,C.J.
  26. 日本營養食糧學會誌 v.37 ラットの食餌性 高コレステロル血症に及ぼすスピルリナ(Spirulina platensis)影響 加騰敏光;竹本和夫;片山博雄;桑原洋子