Ultrastructural Pattern of Synapses in the Rat Olfactory Bulb during Postnatal Development

성장기 흰쥐의 후각망울에서 신경연접의 구조적 변동

  • Rho, Sook-Young (Department of Anatomy, College of Medicine, Ewha Womans University) ;
  • Lee, Hee-Lai (Department of Anatomy, College of Medicine, Ewha Womans University)
  • 노숙영 (이화여자대학교 의과대학 해부학교실) ;
  • 이희래 (이화여자대학교 의과대학 해부학교실)
  • Published : 1994.12.01


This study was undertaken to study the morphological changes of rat synapses during early postnatal periods. Neonatal rats were grouped by 1st, 2nd, 3rd, 4th and 6th postnatal weeks, and we observed the ultrastructural pattern of the synapses in the external plexiform layer of olfactory bulbs by electron microscopy. The results were as follows; 1. The numbers of synapses, lengths of synaptic thickenings and amounts of synaptic vesicles were markedly increased in the external plexiform layer during four postnatal weeks. 2. There was a tendency of increasing the proportion of the asymmetric synapse and the curved synapses during maturation. From the above results, it is suggested that the size of synapse is increasing during maturation, and at the same time the asymmetric synapses are formed from the symmetric type and the curved synapses are from the plane type.