Acute and subacute toxicity of folpet to fingerings of common carp, Cyprinus carpio and goldfish, Carassius auratus

잉어치어(稚魚)와 금붕어에 대한 folpet의 급성(急性) 및 아급성독성(亞急性毒性)에 관한 연구

  • Heo, Gang-joon (Department of Veterinary Medicine, Chungbuk National University) ;
  • Lee, Yong-soon (College of Veterinary Medicine, Seoul National University) ;
  • Lim, Yoon-kyu (Department of Veterinary Medicine, Cheju National University)
  • 허강준 (충북대학교 수의과대학 수의학과 어류질병학연구실) ;
  • 이영순 (서울대학교 수의과대학) ;
  • 임윤규 (제주대학교 농과대학 수의학과)
  • Received : 1994.03.02
  • Published : 1994.04.30

Abstract

The acute and subacute toxicity of fungicide folpet was evaluated in fingerings of common carp, Cyprinus carpio and goldfish, Carrassius auratus. Dipping of fishes for acute toxicity was performed for a period of 24h, and the TLm value(median tolerance limit) was 1.52 ppm in common carp and 1.45 ppm in goldfish. Severe damages were observed in various organs and among them, clubbing of gill lamella, lytic degeneration and vacuolation of liver cells, and epithelial edema of renal tubules were relatively prominent. The most significant changes were hyperbasophilic foci of liver cells in subacute toxicity test and these can imply the possibility of hepatocarcinogenecity of folpet.