A study on efficacy and safety of Bio-Gammamix by oral administratiion to cultured fish

양식어류에 있어서 생약제제(바이오감마믹스)의 경구투여에 의한 효능 및 안전성에 관한 연구

  • Heo, Gang-joon (Laboratory of Aquatic Animal Disease, College of Veterinary Medicine, Chungbuk National University) ;
  • Kim, Byeung-gie (Bayer Veterinary Medical Research Institute, Bayer Vetchem(Korea), Ltd.) ;
  • Yeh, Jae-gill (Bayer Veterinary Medical Research Institute, Bayer Vetchem(Korea), Ltd.) ;
  • kim, Jeong-ho (Bayer Veterinary Medical Research Institute, Bayer Vetchem(Korea), Ltd.)
  • 허강준 (충북대학교 수의과대학 어류질병학연구실) ;
  • 김병기 (한국바이엘화학(주) 바이엘동물의학연구소) ;
  • 예제길 (한국바이엘화학(주) 바이엘동물의학연구소) ;
  • 김정호 (한국바이엘화학(주) 바이엘동물의학연구소)
  • Received : 1994.07.15
  • Published : 1994.07.30

Abstract

A study on efficacy and safety of Bio-Gammamix was performed to use for the preventive drug against bacterial diseases to mirror carp(Cyprinus carpio), rainbow trout(Salmo gairdneri), eel(Anguilla japonica) and flounder(Paralichthys olivaceus). The main ingredients of Bio-Gammamix were ferrous fumarate and mixed extrated powders of licorice root, ox bile and garlic. The test drug was proved to improve feeding habit and feed efficiency and decrease cumulative mortality remarkably. After administration, no side effects and histopathological changes were observed. We can prevent outbreaks of bacterial diseases of fish by the dosage of 1kg/ton of fish body weight perorally once or two times in a day for 7 days and Bio-Gammamix is thought to be used effectively an widely against most bacterial fish pathogens.