Immunohistochemical study on the insulin-, glucagon-, somatostatin-, and pancreatic polypeptide secreting cells in Korean native goat

한국재래산양 췌장의 insulin, glucagon, somatostatin 및 pancreatic polypeptide 분비세포에 관한 면역조직화학적 연구

  • Lee, Heungshik S. (College of Veterinary Medicine, Seoul National University) ;
  • Lee, In-se (College of Veterinary Medicine, Seoul National University) ;
  • Kang, Tae-cheon (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Jin-sang (College of Rehabilitation Science, Taegu University) ;
  • Yi, Seong-joon (College of Veterinary Medicine, Kyungpook National University)
  • 이흥식 (서울대학교 수의과대학) ;
  • 이인세 (서울대학교 수의과대학) ;
  • 강태천 (서울대학교 수의과대학) ;
  • 김진상 (대구대학교 재활과학대학) ;
  • 이성준 (경북대학교 수의과대학)
  • Received : 1994.12.01
  • Published : 1995.01.31

Abstract

Pancreatic endocrine cells containing glucagon, insulin, somatostatin and pancreatic polypeptide were identified in the pancreas of the Korean native goat by using immunohistochemical method. Glucagon immunoreative cells were oval or fusiform in shape and located at the periphery of the pancreatic islets. Insulin immunoreactive cells were round or oval in shape and occupied throughout the pancreatic islets except the small area of the periphery. Somatostatin immunoreative cells were oval and elliptical, and mainly located at the periphery of the pancreatic islets. Some of these cells had a cytoplasmic process. Pancreatic polypeptide immunoreactive cells were elliptical or polyhedral and located at the periphery of the pancratic islets where two or more cells formed a cell cluster. The distribution rates of glucagon, insulin, somatostatin and pancreatic polypeptide immunoreactive cells were 24.4%, 44.3%, 13.2% and 18.1% respectively.

Acknowledgement

Supported by : Korea Science and Engineering Foundation